MPM BioImpact LLC — 13F Holdings

2026 Q1  ·  49 Positions

2026 Q1 Portfolio Activity

In 2026 Q1, MPM BioImpact LLC maintained a portfolio of 49 distinct positions. The most significant new addition was Aktis Oncology, Inc., now representing 6.68% of the total fund value. They heavily accumulated shares in DBV Technologies S A, increasing the position by 423.0%. Conversely, MPM BioImpact LLC completely exited their position in Madrigal Pharmaceuticals Inc.
Position History hover any row below to update
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MPM BioImpact LLC Boston, MA Venture Capital / Life Sciences Specialist AUM $1,295M
PCA Score Concentration Risk
Risk ENB
Total Positions
49
Quarter
2026 Q1
Top Holding
DBVT (8.4%)
Top 10 Concentration
49.0%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-49 of 49

MPM BioImpact LLC Full Holdings List — 2026 Q1

Stock History Sector / Type Port % Prev % Rank / Prev Conviction
Freshness
Change % Change Influence Shares Mkt Value Avg Cost Price Held 1st Owned Source Source Date Date Reported
DBVT
DBV Technologie...
Healthcare 8.41% 2.19% #1 19
Prev: #20
8.4
4,216,536 423.0%
P
S
5,213,361 $108,907,111 2025 Q2 13F Filing 2026-03-31 2026-05-15
CGEM
Cullinan Therap...
Healthcare 8.39% 9.06% #2 1
Prev: #1
5.9
no change no change
P
S
7,648,268 $108,681,888 2021 Q1 13F Filing 2026-03-31 2026-05-15
N/A
Aktis Oncology,...
Unknown 6.68% #3
Prev: #—
7.2
4,835,872
NEW
4,835,872 $86,513,750 13F Filing 2026-03-31 2026-05-15
LQDA
Liquidia Corpor...
Healthcare 4.10% 5.53% #4 1
Prev: #3
2.6
4,289 0.3%
P
S
1,405,158 $53,030,663 2025 Q3 13F Filing 2026-03-31 2026-05-15
ALMS
Alumis Inc
Healthcare 4.06% 2.68% #5 9
Prev: #14
2.6
-15,463 -0.6%
P
S
2,386,529 $52,575,234 2025 Q4 13F Filing 2026-03-31 2026-05-15
EWTX
Edgewise Therap...
Healthcare 4.04% 4.70% #6 1
Prev: #5
2.1
5,440 0.3%
P
S
1,660,696 $52,311,924 2022 Q3 13F Filing 2026-03-31 2026-05-15
RVMD
Revolution Medi...
Healthcare 3.81% 4.61% #7 1
Prev: #6
2.0
1,104 0.2%
P
S
506,776 $49,283,966 2021 Q3 13F Filing 2026-03-31 2026-05-15
AGIO
Agios Pharmaceu...
Healthcare 3.41% 4.06% #8 1
Prev: #7
1.9
2,888 0.2%
P
S
1,306,261 $44,190,810 2025 Q4 13F Filing 2026-03-31 2026-05-15
CORT
Corcept Therape...
Healthcare 3.07% #9
Prev: #—
4.7
985,700
NEW
985,700 $39,733,567 2026 Q1 13F Filing 2026-03-31 2026-05-15
TRVI
Trevi Therapeut...
Healthcare 3.04% 4.71% #10 6
Prev: #4
1.7
11,343 0.3%
P
S
3,298,430 $39,350,270 2024 Q1 13F Filing 2026-03-31 2026-05-15
DNTH
Dianthus Therap...
Healthcare 2.75% #11
Prev: #—
4.6
423,982
NEW
423,982 $35,580,569 2026 Q1 13F Filing 2026-03-31 2026-05-15
XENE
Xenon Pharmaceu...
Healthcare 2.64% 2.49% #12 4
Prev: #16
3.6
103,086 21.2%
P
S
588,706 $34,233,254 2024 Q3 13F Filing 2026-03-31 2026-05-15
MLTX
MoonLake Immuno...
Healthcare 2.61% #13
Prev: #—
4.5
1,811,082
NEW
1,811,082 $33,758,568 2023 Q2 13F Filing 2026-03-31 2026-05-15
TVTX
Travere Therape...
Healthcare 2.60% #14
Prev: #—
4.5
1,133,365
NEW
1,133,365 $33,672,274 2021 Q3 13F Filing 2026-03-31 2026-05-15
EVMN
Evommune Inc
Healthcare 2.58% 0.22% #15 21
Prev: #36
4.0
1,342,841 1188.1%
P
S
1,455,863 $33,470,290 2025 Q4 13F Filing 2026-03-31 2026-05-15
CYTK
Cytokinetics In...
Healthcare 2.54% #16
Prev: #—
4.5
500,000
NEW
500,000 $32,955,000 2021 Q3 13F Filing 2026-03-31 2026-05-15
SNDX
Syndax Pharmace...
Healthcare 2.42% 3.22% #17 7
Prev: #10
1.5
3,031 0.2%
P
S
1,340,733 $31,319,523 2025 Q3 13F Filing 2026-03-31 2026-05-15
CNTX
Context Therape...
Healthcare 2.16% 1.80% #18 8
Prev: #26
1.9
no change no change
P
S
10,679,391 $27,980,004 2024 Q4 13F Filing 2026-03-31 2026-05-15
FBRX
Forte Bioscienc...
Healthcare 2.00% #19
Prev: #—
4.3
1,000,682
NEW
1,000,682 $25,917,664 2026 Q1 13F Filing 2026-03-31 2026-05-15
PVLA
Palvella Therap...
Healthcare 1.99% 2.46% #20 3
Prev: #17
1.3
659 0.3%
P
S
206,404 $25,728,259 2025 Q3 13F Filing 2026-03-31 2026-05-15
DYN
Dyne Therapeuti...
Healthcare 1.97% 3.15% #21 10
Prev: #11
1.3
2,764 0.2%
P
S
1,408,152 $25,529,796 2025 Q2 13F Filing 2026-03-31 2026-05-15
STOK
Stoke Therapeut...
Healthcare 1.93% 2.80% #22 9
Prev: #13
1.3
-3,251 -0.4%
P
S
767,038 $24,974,757 2024 Q3 13F Filing 2026-03-31 2026-05-15
CRVS
Corvus Pharmace...
Healthcare 1.89% 2.42% #23 4
Prev: #19
0.8
-1,068,796 -39.0%
P
S
1,674,875 $24,503,421 2025 Q4 13F Filing 2026-03-31 2026-05-15
RLAY
Relay Therapeut...
Healthcare 1.81% 2.16% #24 3
Prev: #21
2.7
127,135 5.7%
P
S
2,359,586 $23,477,881 2023 Q1 13F Filing 2026-03-31 2026-05-15
TARS
Tarsus Pharmace...
Healthcare 1.79% 3.08% #25 13
Prev: #12
1.2
881 0.3%
P
S
329,750 $23,131,963 2025 Q2 13F Filing 2026-03-31 2026-05-15
ORIC
Oric Pharmaceut...
Healthcare 1.77% 1.68% #26 3
Prev: #29
1.2
5,228 0.3%
P
S
1,803,945 $22,855,983 2025 Q1 13F Filing 2026-03-31 2026-05-15
QURE
Uniqure NV
Healthcare 1.73% 3.78% #27 19
Prev: #8
1.2
-12,397 -0.9%
P
S
1,369,231 $22,386,927 2022 Q4 13F Filing 2026-03-31 2026-05-15
GLUE
Monte Rosa Ther...
Healthcare 1.50% 2.11% #28 6
Prev: #22
1.1
3,552 0.3%
P
S
1,176,928 $19,360,466 2025 Q4 13F Filing 2026-03-31 2026-05-15
NTRA
Natera Inc
Healthcare 1.44% 2.45% #29 11
Prev: #18
1.1
-477 -0.5%
P
S
93,074 $18,613,869 2024 Q1 13F Filing 2026-03-31 2026-05-15
CLYM
Climb Bio Inc
Healthcare 1.37% 1.22% #30 2
Prev: #32
1.0
-78,041 -2.9%
P
S
2,593,439 $17,765,057 2025 Q4 13F Filing 2026-03-31 2026-05-15
ARQT
Arcutis Biother...
Healthcare 1.34% 1.77% #31 4
Prev: #27
3.0
202,766 38.2%
P
S
733,966 $17,292,239 2022 Q1 13F Filing 2026-03-31 2026-05-15
URGN
Urogen Pharma L...
Healthcare 1.31% 2.52% #32 17
Prev: #15
1.0
2,425 0.3%
P
S
943,803 $16,969,578 2025 Q3 13F Filing 2026-03-31 2026-05-15
DRUG
Bright Minds Bi...
Healthcare 1.20% 2.06% #33 10
Prev: #23
1.0
-17,972 -7.8%
P
S
212,175 $15,482,410 2025 Q4 13F Filing 2026-03-31 2026-05-15
ZYME
Zymeworks, Inc.
Healthcare 1.09% #34
Prev: #—
3.9
565,249
NEW
565,249 $14,153,835 2026 Q1 13F Filing 2026-03-31 2026-05-15
BLTE
Belite Bio Inc
Healthcare 1.08% 1.61% #35 5
Prev: #30
0.9
285 0.3%
P
S
88,045 $14,037,895 2025 Q4 13F Filing 2026-03-31 2026-05-15
VRDN
Viridian Therap...
Healthcare 0.98% #36
Prev: #—
3.9
649,873
NEW
649,873 $12,711,516 2023 Q2 13F Filing 2026-03-31 2026-05-15
ENGN
enGene Holdings...
Healthcare 0.97% 1.90% #37 12
Prev: #25
0.9
4,475 0.2%
P
S
1,845,373 $12,566,990 2025 Q3 13F Filing 2026-03-31 2026-05-15
ABVX
Abivax SA
Healthcare 0.92% 0.87% #38 5
Prev: #33
3.4
50,952 90.5%
P
S
107,268 $11,944,292 2025 Q4 13F Filing 2026-03-31 2026-05-15
ALLO
Allogene Therap...
Healthcare 0.42% #39
Prev: #—
3.7
2,242,933
NEW
2,242,933 $5,472,757 2026 Q1 13F Filing 2026-03-31 2026-05-15
ACRS
Aclaris Therape...
Healthcare 0.11% #40
Prev: #—
3.5
391,918
NEW
391,918 $1,469,693 2026 Q1 13F Filing 2026-03-31 2026-05-15
HOWL
Werewolf Therap...
Healthcare 0.08% 0.10% #41 3
Prev: #38
0.5
-184,747 -13.3%
P
S
1,208,810 $1,006,455 2021 Q2 13F Filing 2026-03-31 2026-05-15
SRPT
Sarepta Therape...
Healthcare 0.00% 0.17%
Sold All 😨
(Was: #37)
0.0
-70,000 -100.0%
CLOSED
$— 2025 Q2 13F Filing 2026-03-31 2026-05-15
MAZE
Maze Therapeuti...
Healthcare 0.00% 0.38%
Sold All 😨
(Was: #35)
0.0
-81,145 -100.0%
CLOSED
$— 2025 Q4 13F Filing 2026-03-31 2026-05-15
RCKT
Rocket Pharmace...
Healthcare 0.00% 0.64%
Sold All 😨
(Was: #34)
0.0
-1,586,076 -100.0%
CLOSED
$— 2024 Q3 13F Filing 2026-03-31 2026-05-15
RAPT
RAPT Therapeuti...
Healthcare 0.00% 1.54%
Sold All 😨
(Was: #31)
0.0
-397,906 -100.0%
CLOSED
$— 2025 Q4 13F Filing 2026-03-31 2026-05-15
VTYX
Ventyx Bioscien...
Healthcare 0.00% 1.69%
Sold All 😨
(Was: #28)
0.0
-1,639,061 -100.0%
CLOSED
$— 2023 Q2 13F Filing 2026-03-31 2026-05-15
PTGX
Protagonist The...
Healthcare 0.00% 1.99%
Sold All 😨
(Was: #24)
0.0
-199,471 -100.0%
CLOSED
$— 2025 Q4 13F Filing 2026-03-31 2026-05-15
PTCT
PTC Therapeutic...
Healthcare 0.00% 3.74%
Sold All 😨
(Was: #9)
0.0
-430,013 -100.0%
CLOSED
$— 2024 Q3 13F Filing 2026-03-31 2026-05-15
MDGL
Madrigal Pharma...
Healthcare 0.00% 6.45%
Sold All 😨
(Was: #2)
0.0
-96,780 -100.0%
CLOSED
$— 2022 Q2 13F Filing 2026-03-31 2026-05-15
Showing 1-49 of 49 holdings

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