Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Annexon Inc (ANNX)

213 + Investors. Track Smart Money conviction in ANNX. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +50
Streak
3Q ▲
Buyers last Q
70%

Smart Money Signals — ANNX

Based on 214 hedge funds · latest filing: 2026 Q1 · updated quarterly

📈

Buying streak — 3 quarters in a row

last 6Q
For 3 consecutive quarters, more hedge funds added ANNX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
214 hedge funds hold ANNX right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
🚀

Fast accumulation — +45% more funds vs a year ago

fund count last 6Q
+66 new funds entered over the past year (+45% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.
🟢

More buyers than sellers — 70% buying

153 buying67 selling
Last quarter: 153 funds were net buyers (66 opened a brand new position + 87 added to an existing one). Only 67 were sellers (51 trimmed + 16 sold completely). A clear majority buying is a strong confirmation signal.
📈

More new buyers each quarter (+26 vs last Q)

new funds entering per quarter
Funds opening a new ANNX position: 17 → 36 → 40 → 66. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
📌

Mixed — 37% long-term, 34% new

■ 37% conviction (2yr+) ■ 29% medium ■ 34% new
Of the 214 current holders: 80 (37%) held >2 years, 62 held 1–2 years, and 72 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.
🚀

Acceleration phase — new buyers rushing in

25 → 17 → 36 → 40 → 66 new funds/Q
New funds entering each quarter: 17 → 36 → 40 → 66. The pace of institutional discovery is accelerating sharply. This is the 'hot idea' phase — the thesis is being passed from fund to fund. You are not late — the accumulation wave is still building.
🏛️

Veteran-anchored — 50% veterans vs 34% newcomers

■ 50% veterans ■ 16% 1-2yr ■ 34% new
Entry-cohort mix of 222 holders: 110 (50%) are 2+ year veterans, 36 entered 1–2 years ago, and 76 (34%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
✅

Strong quality — 30% AUM from major funds

30% from top-100 AUM funds
44 of 214 holders rank in the top 100 by AUM, accounting for 30% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.
4.5
out of 10
Moderate Exit Risk
Exit risk score 4.5/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — ANNX

In 2026 Q1, 153 hedge funds were net buyers of ANNX (66 opened a new position, 87 added to an existing one), while 67 reduced or exited (51 trimmed, 16 sold completely) — a 70% buyer ratio, indicating clear institutional accumulation. This marks 3 consecutive quarters of net institutional buying — a persistent conviction signal. 30% of total institutional value in ANNX is held by top-100 AUM funds, reflecting strong institutional quality. Net fund flow last quarter: +50 funds (more new holders than closures). Total institutional holders: 214.

Hedge Fund Ownership: ANNX

How many hedge funds hold ANNX — quarterly history vs. share price
Quarterly hedge fund ownership of ANNX vs. share price

Market Analysis: ANNX

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: ANNX

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Is It Too Late to Buy Annexon Inc (ANNX) Based on Hedge Fund 13F Filings?

Signal Freshness measures how much ANNX has moved relative to its sector benchmark (XLV) since the 2026 Q1 13F filing. A stock that has barely outrun its sector is still a relatively fresh entry point — the fund's thesis has not yet been priced in by the broader market.

Since Quarter End March 31, 2026 · 85d ago
ANNX
-4.7%
XLV
+2.8%

ANNX outperformed XLV by -7.5% since March 31, 2026.

Since 13F Filing Date May 15, 2026 · 40d ago
ANNX
+1.3%
XLV
+3.9%

Since the filing became public, ANNX outperformed XLV by -2.6% .

Interpretation: The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference. Learn more →

Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

23 top-rated funds 2 high-conviction
Consensus
6.0
/ 10
breadth
×
Elite
2.8
/ 10
conviction
Hedge Fund Positioning: ANNX
213 + Investors

Track Smart Money conviction in ANNX. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q1) Prior (2025 Q4) Change
Funds Holding 213 164 29.88%
13F Shares 157M 138M 13.55%
Total Value $860M $690M 24.62%
New Positions 65 40 +25
Increased Positions 85 71 +14
Closed Positions 16 20 -4
Reduced Positions 48 30 +18
Total Calls 6 5 20.0%
Total Puts 2 4 -50.0%
PUT/CALL Ratio 0.33 0.8 Bullish

Statistics: ANNX

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Valuation Measures Data as of: --

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PEG Ratio (5yr expected) --
Price/Sales (ttm) --
Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

Profitability
Profit Margin --
Return on Assets (ttm) --
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Revenue (ttm) --
Net Income Avi to Common (ttm) --
Diluted EPS (ttm) --
Total Cash (mrq) --
Total Debt/Equity (mrq) --
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Institutional Holders (2026 Q1)

213 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in ANNX. Verified SEC 13F-HR filings.

QUARTER:
Top 25 ANNX holders by conviction (% of portfolio weight) — 2026 Q1 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Redmile Group, LLC 5.34% 14,549,768 $80.6M
2 Mak Capital One LLC 3.86% 4,724,043 $26.2M
3 Great Point Partners LLC 3.18% 2,500,000 $13.8M
4 Bain Capital Life Sciences Investors, LLC 2.60% 5,212,674 $28.9M
5 Palo Alto Investors LP 2.50% 2,948,090 $16.3M
6 Opaleye Management Inc. 1.70% 2,331,761 $12.9M
7 Bvf Inc/Il 1.54% 8,698,173 $48.2M
8 Tetragon Partners GP Ltd 1.39% 1,292,455 $7.2M
9 Ishara Investments LP 0.91% 174,250 $965K
10 Bellevue Group AG 0.68% 5,157,290 $28.6M
11 Siren, L.L.C. 0.61% 3,958,646 $21.9M
12 Rosalind Advisors, Inc. 0.45% 200,000 $1.1M
13 Sirios Capital Management L P 0.39% 575,063 $3.2M
14 Parkman Healthcare Partners LLC 0.39% 674,013 $3.7M
15 Diadema Partners LP 0.33% 353,200 $2.0M
16 Verdad Advisers, LP 0.33% 53,277 $295K
17 Board of Trustees of The Leland Stanford Junior University 0.31% 482,550 $2.7M
18 Silverarc Capital Management, LLC 0.28% 496,461 $2.8M
19 Ikarian Capital, LLC 0.26% 580,244 $3.2M
20 DAFNA Capital Management LLC 0.15% 117,812 $653K
21 Y-Intercept (Hong Kong) Ltd 0.14% 1,319,913 $7.3M
22 AlphaCentric Advisors LLC 0.14% 24,518 $136K
23 Longaeva Partners L.P. 0.13% 620,401 $3.4M
24 Diadema Partners LP 0.13% 132,916 $736K
25 Kennedy Capital Management LLC 0.11% 912,323 $5.1M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Annexon Inc (ANNX)

What does the Smart Money Trend signal show for ANNX?

Buying streak — 3 quarters in a row: For 3 consecutive quarters, more hedge funds added ANNX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for ANNX?

More buyers than sellers — 70% buying: Last quarter: 153 funds were net buyers (66 opened a brand new position + 87 added to an existing one). Only 67 were sellers (51 trimmed + 16 sold completely). A clear majority buying is a strong confirmation signal.

What is the fund quality score for ANNX holders?

Strong quality — 30% AUM from major funds: 44 of 214 holders rank in the top 100 by AUM, accounting for 30% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.

How long have hedge funds held ANNX?

Mixed — 37% long-term, 34% new: Of the 214 current holders: 80 (37%) held >2 years, 62 held 1–2 years, and 72 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.

Is it too late to buy Annexon Inc (ANNX) following the 2026 Q1 hedge fund 13F filings?

As of today, ANNX has moved +1.3% since the 2026 Q1 13F filing date (May 15, 2026), compared to +3.9% for the XLV sector ETF — an outperformance of -2.6%. Since the quarter end (March 31, 2026), ANNX has gained -4.7% vs +2.8% for XLV. The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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