2026 Q3 Portfolio Activity
In 2026 Q3, Affinity Asset Advisors, LLC maintained a portfolio of 146 distinct positions. The most significant new addition was ISHARES TR, now representing 11.31% of the total fund value. They heavily accumulated shares in ALKERMES PLC, increasing the position by 526.0%. Conversely, Affinity Asset Advisors, LLC completely exited their position in APOGEE THERAPEUTICS INC.
Position History
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Total Positions
146
Quarter
2026 Q3
Top Holding
IWM (11.3%)
Top 10 Concentration
41.5%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-50 of 146
Affinity Asset Advisors, LLC Full Holdings List — 2026 Q3
| Stock | History | Sector / Type | Port % | Prev % | Rank / Prev | Conviction | Change | % Change | Influence | Shares | Mkt Value | Avg Cost | Price Held | 1st Owned | Source | Source Date | Date Reported | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
IWM
PUT
ISHARES TR
|
PUT Option | 11.31% | — |
#1
Prev: #—
|
9.5 |
—
|
1,000,000 | — |
NEW
|
1,000,000 | $277,890,000 |
$250.68
+10.7%
|
2022 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | ||
|
ROIV
ROIVANT SCIENCE...
|
Healthcare | 4.76% | 6.00% |
#2
1
Prev: #1
|
3.9 |
—
|
-550,000 | -14.7% |
P
S
|
3,200,000 | $117,024,000 |
$23.84
+65.8%
|
2023 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | ||
|
SYRE
SPYRE THERAPEUT...
|
Healthcare | 4.63% | 5.13% |
#3
Prev: #3
|
3.9 |
—
|
no change | no change |
P
S
|
1,279,134 | $113,881,300 |
$18.36
+466.6%
|
2023 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | ||
|
XBI
PUT
SPDR SERIES TRU...
|
PUT Option | 3.85% | — |
#4
Prev: #—
|
5.5 |
—
|
600,000 | — |
NEW
|
600,000 | $94,608,000 | 2021 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ERAS
ERASCA INC
|
Healthcare | 3.33% | 4.35% |
#5
Prev: #5
|
3.8 |
—
|
340,600 | 6.5% |
P
S
|
5,590,600 | $81,958,196 | 2024 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
TRAX
FIRST TRACKS BI...
|
Healthcare | 3.00% | 1.85% |
#6
9
Prev: #15
|
1.7 |
—
|
47,988 | 2.4% |
P
S
|
2,080,000 | $73,715,200 | 2026 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
XENE
XENON PHARMACEU...
|
Healthcare | 2.88% | 4.35% |
#7
3
Prev: #4
|
3.2 |
—
|
305,374 | 19.1% |
P
S
|
1,900,374 | $70,674,909 | 2021 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
INSM
INSMED INC
|
Healthcare | 2.62% | 3.13% |
#8
2
Prev: #6
|
1.5 |
—
|
-85,749 | -13.2% |
P
S
|
564,251 | $64,403,609 | 2024 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ALKS
ALKERMES PLC
|
Healthcare | 2.58% | 2.66% |
#9
1
Prev: #8
|
3.5 |
—
|
440,000 | 39.1% |
P
S
|
1,565,000 | $63,413,800 | 2023 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
MRNA
PUT
MODERNA INC
|
PUT Option | 2.55% | 1.58% |
#10
8
Prev: #18
|
1.0 |
—
|
-175,000 | -35.0% |
P
S
|
325,000 | $62,585,250 | 2021 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ARKG
PUT
ARK ETF TR
|
PUT Option | 2.21% | — |
#11
Prev: #—
|
4.4 |
—
|
1,000,000 | — |
NEW
|
1,000,000 | $54,220,000 | 2020 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ARKG
CALL
ARK ETF TR
|
CALL Option | 2.10% | 1.43% |
#12
10
Prev: #22
|
3.3 |
—
|
200,000 | 26.7% |
P
S
|
950,000 | $51,509,000 | 2020 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ORKA
ORUKA THERAPEUT...
|
Healthcare | 2.03% | 2.54% |
#13
4
Prev: #9
|
1.3 |
—
|
10,000 | 1.7% |
P
S
|
600,000 | $49,974,000 | 2024 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
AVTX
AVALO THERAPEUT...
|
Healthcare | 2.02% | 2.42% |
#14
3
Prev: #11
|
2.8 |
—
|
344,861 | 11.9% |
P
S
|
3,244,861 | $49,743,719 | 2024 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
CYTK
CYTOKINETICS IN...
|
Healthcare | 2.01% | 2.12% |
#15
3
Prev: #12
|
3.3 |
—
|
200,000 | 36.4% |
P
S
|
750,000 | $49,432,500 | 2020 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
MRNA
CALL
MODERNA INC
|
CALL Option | 1.96% | 1.50% |
#16
5
Prev: #21
|
0.8 |
—
|
-225,000 | -47.4% |
P
S
|
250,000 | $48,142,500 | 2021 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
RVMD
REVOLUTION MEDI...
|
Healthcare | 1.88% | 2.12% |
#17
4
Prev: #13
|
1.3 |
—
|
-25,000 | -10.0% |
P
S
|
225,000 | $46,183,500 | 2025 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
PRAX
PRAXIS PRECISIO...
|
Healthcare | 1.84% | 2.80% |
#18
11
Prev: #7
|
1.2 |
—
|
-30,000 | -16.2% |
P
S
|
155,000 | $45,140,650 | 2025 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
BLTE
BELITE BIO INC
|
Healthcare | 1.67% | 1.15% |
#19
7
Prev: #26
|
3.2 |
—
|
77,088 | 46.7% |
P
S
|
242,088 | $41,111,384 | 2025 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
IBRX
PUT
IMMUNITYBIO INC
|
PUT Option | 1.66% | — |
#20
Prev: #—
|
4.2 |
—
|
4,308,700 | — |
NEW
|
4,308,700 | $40,674,128 | 2024 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
CLDX
CELLDEX THERAPE...
|
Healthcare | 1.53% | 1.18% |
#21
4
Prev: #25
|
3.6 |
—
|
460,499 | 65.8% |
P
S
|
1,160,499 | $37,611,773 | 2020 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ABVX
ABIVAX SA
|
Healthcare | 1.33% | 1.99% |
#22
8
Prev: #14
|
1.5 |
—
|
no change | no change |
P
S
|
330,000 | $32,676,600 | 2025 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
DNTH
DIANTHUS THERAP...
|
Healthcare | 1.25% | 1.76% |
#23
7
Prev: #16
|
1.0 |
—
|
-50,000 | -12.5% |
P
S
|
350,000 | $30,817,500 | 2025 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
SMMT
PUT
SUMMIT THERAPEU...
|
PUT Option | 1.17% | — |
#24
Prev: #—
|
4.0 |
—
|
1,700,000 | — |
NEW
|
1,700,000 | $28,747,000 | 2024 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ODTX
ODYSSEY THERAPE...
|
Healthcare | 1.14% | 0.65% |
#25
19
Prev: #44
|
3.5 |
—
|
493,654 | 64.4% |
P
S
|
1,260,000 | $27,997,200 | 2026 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ARWR
ARROWHEAD PHARM...
|
Healthcare | 1.13% | 0.55% |
#26
28
Prev: #54
|
3.5 |
—
|
275,000 | 183.3% |
P
S
|
425,000 | $27,816,250 | 2024 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
TRVI
TREVI THERAPEUT...
|
Healthcare | 1.05% | 1.52% |
#27
7
Prev: #20
|
1.4 |
—
|
no change | no change |
P
S
|
1,800,172 | $25,778,463 | 2025 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
OVID
OVID THERAPEUTI...
|
Healthcare | 1.03% | 1.23% |
#28
5
Prev: #23
|
1.4 |
—
|
no change | no change |
P
S
|
10,144,562 | $25,259,959 | 2025 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
SGMT
SAGIMET BIOSCIE...
|
Healthcare | 1.02% | 0.87% |
#29
7
Prev: #36
|
0.9 |
—
|
29,520 | 1.2% |
P
S
|
2,527,384 | $24,970,554 | 2025 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ALKS
CALL
ALKERMES PLC
|
CALL Option | 1.01% | 0.59% |
#30
19
Prev: #49
|
3.4 |
—
|
365,400 | 146.2% |
P
S
|
615,400 | $24,936,008 | 2023 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
LXEO
LEXEO THERAPEUT...
|
Healthcare | 1.00% | 1.22% |
#31
7
Prev: #24
|
2.9 |
—
|
1,438,000 | 24.8% |
P
S
|
7,245,611 | $24,490,165 | 2025 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
PTGX
PROTAGONIST THE...
|
Healthcare | 0.99% | 0.95% |
#32
1
Prev: #33
|
1.4 |
—
|
no change | no change |
P
S
|
172,125 | $24,250,691 | 2021 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
NRIX
NURIX THERAPEUT...
|
Healthcare | 0.93% | 1.06% |
#33
3
Prev: #30
|
1.4 |
—
|
no change | no change |
P
S
|
967,620 | $22,942,270 | 2022 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
N/A
OMEROS CORP
|
|
Bond/Debt | 0.86% | 0.55% |
#34
21
Prev: #55
|
1.3 |
—
|
no change | no change |
P
S
|
6,525,000 | $21,205,656 | — | 13F Filing | 2026-09-30 | 2026-11-13 | ||
|
VOGX
VOGENX INC
|
Healthcare | 0.85% | — |
#35
Prev: #—
|
3.8 |
—
|
915,000 | — |
NEW
|
915,000 | $20,852,850 | 2026 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
MLYS
MINERALYS THERA...
|
Healthcare | 0.77% | 0.91% |
#36
2
Prev: #34
|
1.3 |
—
|
no change | no change |
P
S
|
750,000 | $18,847,500 | 2023 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
TYRA
TYRA BIOSCIENCE...
|
Healthcare | 0.76% | 0.29% |
#37
34
Prev: #71
|
3.3 |
—
|
649,988 | 325.0% |
P
S
|
850,000 | $18,589,500 | 2026 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
STRO
SUTRO BIOPHARMA...
|
Healthcare | 0.76% | 1.76% |
#38
21
Prev: #17
|
0.8 |
—
|
-20,000 | -1.7% |
P
S
|
1,152,487 | $18,566,566 | 2020 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
TVTX
TRAVERE THERAPE...
|
Healthcare | 0.72% | 0.77% |
#39
Prev: #39
|
1.3 |
—
|
no change | no change |
P
S
|
300,000 | $17,664,000 | 2021 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ANRO
ALTO NEUROSCIEN...
|
Healthcare | 0.67% | 1.01% |
#40
9
Prev: #31
|
0.3 |
—
|
-206,657 | -24.3% |
P
S
|
643,343 | $16,424,547 | 2026 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
ARVN
ARVINAS INC
|
Healthcare | 0.65% | — |
#41
Prev: #—
|
3.8 |
—
|
2,050,000 | — |
NEW
|
2,050,000 | $15,856,750 | 2024 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
EPRX
EUPRAXIA PHARMA...
|
Healthcare | 0.64% | 0.49% |
#42
16
Prev: #58
|
0.8 |
—
|
66,320 | 4.0% |
P
S
|
1,716,320 | $15,618,512 | 2025 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
RLAY
RELAY THERAPEUT...
|
Healthcare | 0.62% | 0.89% |
#43
8
Prev: #35
|
0.7 |
—
|
-200,000 | -19.0% |
P
S
|
850,000 | $15,342,500 | 2022 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
MDGL
MADRIGAL PHARMA...
|
Healthcare | 0.62% | 0.97% |
#44
12
Prev: #32
|
0.2 |
—
|
-10,000 | -25.0% |
P
S
|
30,000 | $15,118,800 | 2020 Q4 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
CGEM
CULLINAN THERAP...
|
Healthcare | 0.55% | 0.72% |
#45
5
Prev: #40
|
1.2 |
—
|
no change | no change |
P
S
|
875,760 | $13,442,916 | 2021 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
SVRA
SAVARA INC
|
Healthcare | 0.53% | 0.70% |
#46
5
Prev: #41
|
1.2 |
—
|
no change | no change |
P
S
|
2,512,153 | $12,962,709 | 2023 Q3 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
COAG
HEMAB THERAPEUT...
|
Healthcare | 0.53% | 0.23% |
#47
33
Prev: #80
|
3.2 |
—
|
281,970 | 204.3% |
P
S
|
420,000 | $12,952,800 | 2026 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
N/A
COGENT BIOSCIEN...
|
|
Bond/Debt | 0.49% | 0.62% |
#48
3
Prev: #45
|
1.2 |
—
|
no change | no change |
P
S
|
11,000,000 | $12,054,793 | — | 13F Filing | 2026-09-30 | 2026-11-13 | ||
|
CLYM
CLIMB BIO INC
|
Healthcare | 0.45% | 0.57% |
#49
2
Prev: #51
|
1.2 |
—
|
no change | no change |
P
S
|
972,000 | $11,148,840 | 2024 Q2 | 13F Filing | 2026-09-30 | 2026-11-13 | |||
|
IBRX
IMMUNITYBIO INC
|
Healthcare | 0.45% | — |
#50
Prev: #—
|
3.7 |
—
|
1,180,000 | — |
NEW
|
1,180,000 | $11,139,200 | 2024 Q1 | 13F Filing | 2026-09-30 | 2026-11-13 |
Showing 1-50 of 146 holdings