Insmed Inc (INSM): Hedge Fund Ownership & Smart Money Signals (Q1 2026)

Q: Is it too late to buy Insmed Inc (INSM) following the 2026 Q1 hedge fund 13F filings?

As of today, INSM has moved -9.8% since the 2026 Q1 13F filing date (May 15, 2026), compared to +3.2% for the XLV sector ETF — an outperformance of -13.0%. Since the quarter end (March 31, 2026), INSM gained -39.8% vs +2.1% for XLV. The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference.

Insmed Inc (INSM)

667 + Investors. Track Smart Money conviction in INSM. See who's accumulating, reducing, or initiating positions.

Smart Money Signals — INSM

Based on 670 hedge funds · latest filing: 2026 Q1 · updated quarterly

📉

Selling streak — 1 quarter in a row

last 6Q

For 1 consecutive quarter, more hedge funds reduced or closed their INSM positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.

🏔️

At the ownership peak (99% of max)

99% of all-time peak

670 hedge funds hold INSM right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.

🚀

Fast accumulation — +53% more funds vs a year ago

fund count last 6Q

+233 new funds entered over the past year (+53% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.

🟡

Slight buying edge — 55% buying

400 buying324 selling

Last quarter: 400 funds bought or added vs 324 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

⚠️

Fewer new buyers each quarter (-105 vs last Q)

new funds entering per quarter

Funds opening this position for the first time: 128 → 129 → 204 → 99. Each quarter fewer new institutions are entering. This usually means most funds that wanted in are already in — the stock is well-known but the pool of potential new buyers is shrinking.

📌

Mixed — 35% long-term, 38% new

■ 35% conviction (2yr+) ■ 26% medium ■ 38% new

Of the 670 current holders: 236 (35%) held >2 years, 177 held 1–2 years, and 257 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.

📈

Growing discovery — still being found

61 → 128 → 129 → 204 → 99 new funds/Q

New funds entering each quarter: 128 → 129 → 204 → 99. A growing number of institutions are discovering INSM each quarter. The narrative is still spreading — leaving room for ongoing capital accumulation.

🏛️

Veteran-anchored — 42% veterans vs 43% newcomers

■ 42% veterans ■ 15% 1-2yr ■ 43% new

Entry-cohort mix of 701 holders: 296 (42%) are 2+ year veterans, 103 entered 1–2 years ago, and 302 (43%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.

🏆

Elite ownership — 40% AUM from top-100 funds

40% from top-100 AUM funds

65 of 664 holders are among the 100 largest funds by AUM, controlling 40% of total institutional value in INSM. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

4.6

out of 10

Moderate Exit Risk

Exit risk score 4.6/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Metric	All 13F Filers (2026 Q1)	Prior (2025 Q4)	Change
Funds Holding	667	677	-1.48%
13F Shares	196M	221M	-11.29%
Total Value	$30.57B	$37.53B	-18.54%
New Positions	98	204	-106
Increased Positions	286	229	+57
Closed Positions	108	87	+21
Reduced Positions	210	189	+21
Total Calls	18	28	-35.71%
Total Puts	18	23	-21.74%
PUT/CALL Ratio	1.0	0.82	Neutral

Metric

All 13F Filers (2026 Q1)

Prior (2025 Q4)

Change

Funds Holding

667

677

-1.48%

13F Shares

196M

221M

-11.29%

Total Value

$30.57B

$37.53B

-18.54%

New Positions

204

-106

Increased Positions

286

229

+57

Closed Positions

108

+21

Reduced Positions

210

189

+21

Total Calls

-35.71%

Total Puts

-21.74%

PUT/CALL Ratio

1.0

0.82

Neutral

Institutional Holders (2026 Q1)

667 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in INSM. Verified SEC 13F-HR filings.

QUARTER:

FILTER:All New Added To Reduced No Change | Overweight >5%

Top 25 INSM holders by conviction (% of portfolio weight) — 2026 Q1 · Source: SEC Form 13F
#	Investor	% of Portfolio	Shares	Mkt Value
1	Darwin Global Management, Ltd.	68.33%	16,805,184	$2.58B
2	Artia Global Partners LP	20.59%	628,712	$102.8M
3	Integral Health Asset Management, LLC	11.73%	1,500,000	$245.3M
4	Palo Alto Investors LP	10.39%	415,269	$67.9M
5	Artia Global Partners LP	9.16%	279,700	$45.7M
6	Davern Capital Partners, LP	8.19%	182,562	$29.9M
7	Rtw Investments, LP	7.88%	4,842,880	$791.9M
8	Baker BROS. Advisors LP	6.97%	7,421,111	$1.21B
9	Eagle Health Investments LP	6.41%	224,271	$36.7M
10	Patient Square Capital LP	4.57%	157,500	$25.8M
11	First Turn Management, LLC	4.54%	248,475	$40.6M
12	Defilade Capital Management, L.P.	4.48%	194,909	$31.9M
13	Paradigm Biocapital Advisors LP	4.19%	1,254,488	$205.1M
14	Affinity Asset Advisors, LLC	4.05%	480,000	$78.5M
15	KVP Capital Advisors, LP	3.48%	28,497	$4.7M
16	GordonMD Global Investments LP	3.26%	28,587	$4.7M
17	Rhenman & Partners Asset Management AB	3.22%	159,760	$26.1M
18	Rock Springs Capital Management LP	3.03%	314,300	$51.4M
19	Summit Partners Public Asset Management, LLC	2.87%	653,445	$106.9M
20	Sectoral Asset Management Inc	2.80%	19,668	$3.4M
21	Exome Asset Management LLC	2.25%	26,651	$4.4M
22	Tang Capital Management LLC	2.16%	260,000	$42.5M
23	Nicholas Investment Partners, LP	2.15%	182,540	$29.8M
24	Sofinnova Investments, Inc.	2.15%	346,075	$56.6M
25	Atle Fund Management AB	1.92%	97,438	$6.0M

Investor	Ownership History	% of Portfolio	Prev %	Rank	Conviction	Avg Buy Price	13F Score™ 3Y / 7Y	Sell Timing	Shares	Mkt Value	Change	Change %	Source	Quarter	Filed

Frequently Asked Questions — Insmed Inc (INSM)

What does the Smart Money Trend signal show for INSM?

Selling streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds reduced or closed their INSM positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.

What is the institutional breadth score for INSM?

Slight buying edge — 55% buying: Last quarter: 400 funds bought or added vs 324 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for INSM holders?

Elite ownership — 40% AUM from top-100 funds: 65 of 664 holders are among the 100 largest funds by AUM, controlling 40% of total institutional value in INSM. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held INSM?

Mixed — 35% long-term, 38% new: Of the 670 current holders: 236 (35%) held >2 years, 177 held 1–2 years, and 257 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.

Is it too late to buy Insmed Inc (INSM) following the 2026 Q1 hedge fund 13F filings?

As of today, INSM has moved -9.8% since the 2026 Q1 13F filing date (May 15, 2026), compared to +3.2% for the XLV sector ETF — an outperformance of -13.0%. Since the quarter end (March 31, 2026), INSM has gained -39.8% vs +2.1% for XLV. The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

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Insmed Inc (INSM)

Smart Money Signals — INSM

Selling streak — 1 quarter in a row

At the ownership peak (99% of max)

Fast accumulation — +53% more funds vs a year ago

Slight buying edge — 55% buying

Fewer new buyers each quarter (-105 vs last Q)

Mixed — 35% long-term, 38% new

Growing discovery — still being found

Veteran-anchored — 42% veterans vs 43% newcomers

Elite ownership — 40% AUM from top-100 funds

Institutional Sentiment Summary — INSM

Hedge Fund Ownership: INSM

Market Analysis: INSM

Analyst Price Targets

Analyst Recommendations

Stock Performance

Company Profile: INSM

Is It Too Late to Buy Insmed Inc (INSM) Based on Hedge Fund 13F Filings?

Hedge Fund Positioning: INSM

Statistics: INSM

Valuation Measures Data as of: --

Financial Highlights

Institutional Holders (2026 Q1)

Frequently Asked Questions — Insmed Inc (INSM)

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