Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Protagonist Therapeutics Inc (PTGX)

340 + Investors. Track Smart Money conviction in PTGX. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +31
Streak
1Q ▲
Buyers last Q
61%

Smart Money Signals — PTGX

Based on 346 hedge funds · latest filing: 2026 Q2 · updated quarterly

📈

Buying streak — 1 quarter in a row

last 6Q
For 1 consecutive quarter, more hedge funds added PTGX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
346 hedge funds hold PTGX right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
🚀

Fast accumulation — +26% more funds vs a year ago

fund count last 6Q
+72 new funds entered over the past year (+26% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.
🟢

More buyers than sellers — 61% buying

209 buying134 selling
Last quarter: 209 funds were net buyers (73 opened a brand new position + 136 added to an existing one). Only 134 were sellers (92 trimmed + 42 sold completely). A clear majority buying is a strong confirmation signal.
📈

More new buyers each quarter (+21 vs last Q)

new funds entering per quarter
Funds opening a new PTGX position: 44 → 86 → 52 → 73. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔒

40% of holders stayed for 2+ years

■ 40% conviction (2yr+) ■ 31% medium ■ 30% new
137 out of 346 hedge funds have held PTGX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
➡️

Steady discovery — ~73 new funds/quarter

56 → 44 → 86 → 52 → 73 new funds/Q
New funds entering each quarter: 44 → 86 → 52 → 73. Consistent flow of new institutional buyers without clear acceleration or slowdown.
🏛️

Veteran-anchored — 48% veterans vs 35% newcomers

■ 48% veterans ■ 18% 1-2yr ■ 35% new
Entry-cohort mix of 357 holders: 170 (48%) are 2+ year veterans, 63 entered 1–2 years ago, and 124 (35%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
🏆

Elite ownership — 56% AUM from top-100 funds

56% from top-100 AUM funds
55 of 344 holders are among the 100 largest funds by AUM, controlling 56% of total institutional value in PTGX. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.
4.0
out of 10
Moderate Exit Risk
Exit risk score 4.0/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — PTGX

In 2026 Q2, 209 hedge funds were net buyers of PTGX (73 opened a new position, 136 added to an existing one), while 134 reduced or exited (92 trimmed, 42 sold completely) — a 61% buyer ratio, indicating clear institutional accumulation. 56% of total institutional value in PTGX is held by top-100 AUM funds, reflecting elite-tier ownership quality. Net fund flow last quarter: +31 funds (more new holders than closures). Total institutional holders: 346.

Hedge Fund Ownership: PTGX

How many hedge funds hold PTGX — quarterly history vs. share price
Quarterly hedge fund ownership of PTGX vs. share price

Market Analysis: PTGX

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: PTGX

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Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Loading signal freshness…
Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

14 top-rated funds 7 high-conviction
Consensus
5.1
/ 10
breadth
×
Elite
3.8
/ 10
conviction
Hedge Fund Positioning: PTGX
340 + Investors

Track Smart Money conviction in PTGX. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q2) Prior (2026 Q1) Change
Funds Holding 340 315 7.94%
13F Shares 70M 72M -2.88%
Total Value $8.20B $7.34B 11.63%
New Positions 71 52 +19
Increased Positions 131 108 +23
Closed Positions 44 53 -9
Reduced Positions 91 109 -18
Total Calls 7 9 -22.22%
Total Puts 6 6 -
PUT/CALL Ratio 0.86 0.67 Neutral

Statistics: PTGX

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Institutional Holders (2026 Q2)

340 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in PTGX. Verified SEC 13F-HR filings.

QUARTER:
Top 25 PTGX holders by conviction (% of portfolio weight) — 2026 Q2 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Johnson & Johnson 37.59% 2,449,183 $300.2M
2 NEXTBio Capital Management LP 12.37% 219,333 $26.9M
3 ADAR1 Capital Management, LLC 5.39% 960,863 $117.8M
4 Rtw Investments, LP 5.30% 5,061,175 $620.4M
5 Eagle Health Investments LP 5.05% 248,322 $30.4M
6 KVP Capital Advisors, LP 4.77% 53,000 $6.5M
7 Knott David M Jr 4.08% 63,000 $7.7M
8 Catalio Capital Management, LP 2.46% 106,799 $13.1M
9 Birchview Capital, LP 2.01% 35,018 $4.3M
10 NAN FUNG TRINITY (HK) Ltd 1.94% 160,670 $19.7M
11 Perceptive Advisors LLC 1.81% 981,879 $120.4M
12 683 Capital Management, LLC 1.75% 290,000 $35.5M
13 Boxer Capital Management, LLC 1.57% 170,000 $20.8M
14 Moody Aldrich Partners LLC 1.31% 59,601 $7.3M
15 Elmind Capital, LP 1.17% 38,000 $4.7M
16 Opaleye Management Inc. 1.11% 100,000 $12.3M
17 Affinity Asset Advisors, LLC 0.95% 172,125 $21.1M
18 AlphaCentric Advisors LLC 0.95% 9,171 $1.1M
19 Seven Fleet Capital Management LP 0.92% 45,400 $5.6M
20 Hood River Capital Management LLC 0.78% 882,738 $108.2M
21 HighVista Strategies LLC 0.68% 24,460 $3.0M
22 Woodline Partners LP 0.54% 1,414,173 $173.3M
23 Driehaus Capital Management LLC 0.52% 731,053 $89.6M
24 Artia Global Partners LP 0.52% 22,951 $2.8M
25 Atika Capital Management LLC 0.50% 62,100 $7.6M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Protagonist Therapeutics Inc (PTGX)

What does the Smart Money Trend signal show for PTGX?

Buying streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds added PTGX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for PTGX?

More buyers than sellers — 61% buying: Last quarter: 209 funds were net buyers (73 opened a brand new position + 136 added to an existing one). Only 134 were sellers (92 trimmed + 42 sold completely). A clear majority buying is a strong confirmation signal.

What is the fund quality score for PTGX holders?

Elite ownership — 56% AUM from top-100 funds: 55 of 344 holders are among the 100 largest funds by AUM, controlling 56% of total institutional value in PTGX. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held PTGX?

40% of holders stayed for 2+ years: 137 out of 346 hedge funds have held PTGX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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