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Analyst Tracker/Paul Matteis
STIF

Paul Matteis

Wall Street Analyst
★★★★★
#204
on 13Foresight · ranked by our own returns
71%
Success Rate
+26.1%
Average Return
51 of 72 calls profitable · +17.8% vs benchmark
S&P 500 (SPY)
📈 Across the calls we could measure, roughly 71% of Paul Matteis's ratings turned a profit when each position was held for 2 year — averaging +26.1% per rating. These figures are computed by 13Foresight from historical prices, not supplied by the analyst.

Rating Distribution

131 Buy 39 Hold 0 Sell
Paul's Stock Coverage 41 ratings · 2026-08-13
Company Date Position Consensus Price Target 2-Yr Return vs S&P 500
SION
Sionna Therapeutics, Inc.
Aug 10, 2026 HOLD Hold
+159.8% avg upside
12 analysts
$7.00
12.00% Upside
+45.3% ·
VRTX
Vertex Pharmaceuticals
Aug 09, 2026 HOLD Strong Buy
-15.5% avg upside
62 analysts
$500.00
4.96% Downside
+0.4% ·
BMRN
BioMarin Pharmaceutical
Aug 07, 2026 HOLD Strong Buy
+35.2% avg upside
52 analysts
$70.00
0.28% Downside
+8.4% ·
DNLI
Denali Therapeutics
Aug 07, 2026 BUY Strong Buy
+52.6% avg upside
24 analysts
$41.00
62.33% Upside
+1.6% ·
DFTX
Definium Therapeutics
Aug 07, 2026 BUY Strong Buy
+15.8% avg upside
21 analysts
$60.00
40.21% Upside
-5.1% ·
XENE
Xenon
Aug 07, 2026 BUY Strong Buy
-4.0% avg upside
28 analysts
$86.00
31.87% Upside
+1.4% ·
GHRS
GH Research
Aug 06, 2026 BUY Strong Buy
+31.2% avg upside
12 analysts
$38.00
25.63% Upside
-2.1% ·
ACAD
ACADIA Pharmaceuticals
Aug 05, 2026 HOLD Strong Buy
+24.3% avg upside
43 analysts
$25.00
15.15% Downside
-1.5% ·
IONS
Ionis Pharmaceuticals
Aug 02, 2026 HOLD Strong Buy
+40.4% avg upside
43 analysts
$68.00
20.23% Upside
+4.5% ·
BIIB
Biogen
Aug 02, 2026 BUY Strong Buy
+21.4% avg upside
52 analysts
$242.00
15.89% Upside
+3.5% ·
NBIX
Neurocrine
Jul 31, 2026 BUY Strong Buy
+19.2% avg upside
37 analysts
$215.00
37.34% Upside
-6.2% ·
DYN
Dyne Therapeutics
Jul 31, 2026 BUY Strong Buy
+51.5% avg upside
31 analysts
$37.00
41.43% Upside
+3.1% ·
ALNY
Alnylam Pharma
Jul 31, 2026 BUY Strong Buy
+44.8% avg upside
51 analysts
$318.00
42.07% Upside
+10.5% ·
ALKS
Alkermes
Jul 25, 2026 BUY Strong Buy
-17.2% avg upside
34 analysts
$63.00
25.25% Upside
-6.9% ·
CMPS
COMPASS Pathways
Jul 08, 2026 BUY Strong Buy
+57.6% avg upside
20 analysts
$21.00
47.61% Upside
-2.4% ·
VTGN
VistaGen Therapeutics
Jul 06, 2026 HOLD Hold
+901.4% avg upside
8 analysts
$1.00
282.77% Upside
+12.0% ·
LXEO
Lexeo Therapeutics, Inc.
Jul 06, 2026 BUY Strong Buy
+295.1% avg upside
11 analysts
$17.00
249.06% Upside
+7.8% ·
NGNE
Neurogene
Jul 06, 2026 BUY Strong Buy
+32.6% avg upside
23 analysts
$46.00
24.49% Upside
+9.6% ·
QURE
uniQure
Jun 21, 2026 BUY Strong Buy
+31.0% avg upside
29 analysts
$71.00
57.29% Upside
+5.1% ·
RYTM
Rhythm Pharmaceuticals
Jun 15, 2026 BUY Strong Buy
+7.1% avg upside
20 analysts
$133.00
13.06% Upside
+29.3% ·
SPTX
Seaport Therapeutics, Inc.
Jun 09, 2026 BUY Strong Buy
+61.5% avg upside
6 analysts
$30.00
26.12% Upside
+33.8% ·
MPLT
MapLight Therapeutics, Inc.
Jun 02, 2026 BUY Strong Buy
+157.5% avg upside
13 analysts
$36.00
216.29% Upside
-57.6% ·
IMUX
Immunic
May 28, 2026 BUY Strong Buy
+144.1% avg upside
21 analysts
$25.00
56.90% Upside
+9.9% ·
RAPP
Rapport Therapeutics, Inc.
May 12, 2026 BUY Strong Buy
+20.3% avg upside
14 analysts
$56.00
17.40% Upside
+27.6% ·
NMRA
Neumora Therapeutics, Inc.
May 12, 2026 HOLD Buy
+350.0% avg upside
11 analysts
$3.00
75.46% Upside
-8.9% ·
CTNM
Contineum Therapeutics, Inc. Class A
May 08, 2026 BUY Strong Buy
+45.6% avg upside
9 analysts
$28.00
86.93% Upside
+10.5% ·
PEPG
PepGen Inc.
Apr 04, 2026 BUY Strong Buy
+265.4% avg upside
9 analysts
$12.00
313.73% Upside
+53.8% ·
ANRO
Alto Neuroscience, Inc.
Apr 02, 2026 BUY Strong Buy
+4.2% avg upside
13 analysts
$33.00
13.02% Upside
+49.0% ·
LBRX
LB Pharmaceuticals, Inc.
Mar 27, 2026 BUY Strong Buy
+1.7% avg upside
8 analysts
$40.00
11.76% Downside
+85.7% ·
ALEC
Alector
Dec 22, 2025 HOLD Hold
+364.1% avg upside
14 analysts
+40.7% ·
ABOS
Acumen Pharmaceuticals
Dec 16, 2025 BUY Strong Buy
+222.9% avg upside
10 analysts
$10.00
298.46% Upside
+17.1% ·
LONA
LeonaBio
Sep 19, 2024 HOLD Buy
+42.7% avg upside
9 analysts
+69.2% ·
CLYM
Climb Bio
Jun 03, 2023 BUY Strong Buy
+33.3% avg upside
19 analysts
$5.00
65.23% Downside
-56.3% ·
WVE
Wave Life Sciences
May 12, 2022 HOLD Strong Buy
+299.0% avg upside
28 analysts
$3.00
42.79% Downside
+335.7% ·
IRON
Disc Medicine
Feb 28, 2022 HOLD Strong Buy
+7.6% avg upside
21 analysts
$20.00
75.20% Downside
+59.7% ·
OBSEF
ObsEva
Aug 16, 2017 BUY Buy
+10799900.0% avg upside
8 analysts
$18.00
17999899.99% Upside
· ·
NBRVF
Nabriva Therapeutics
Mar 10, 2017 BUY Buy
+13374900.0% avg upside
9 analysts
$20.00
19999899.93% Upside
· ·
ACIU
AC Immune SA
Nov 23, 2016 BUY Strong Buy
+206.6% avg upside
5 analysts
-6.4% ·
FATE
Fate Therapeutics
Jun 20, 2016 BUY Buy
+341.7% avg upside
31 analysts
+574.0% ·
TBPH
Theravance Biopharma
Jun 20, 2016 BUY Buy
+9.0% avg upside
18 analysts
$29.00
71.32% Upside
+8.0% ·
TPST
Tempest Therapeutics
May 06, 2016 HOLD Buy
+1711.4% avg upside
18 analysts
$7.00
478.43% Upside
· ·
🔒 36 more ratings — with price targets, crowd consensus and our measured returns.
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Paul Matteis — Frequently Asked Questions
How accurate are Paul Matteis's stock ratings?
Based on the calls 13Foresight could measure, about 68% of Paul's ratings were profitable over a one-year hold, with an average return of +18.8% per rating, or +12.9% versus the S&P 500. We score every analyst the same way, from historical prices. Each return is measured in the stock's own trading currency, so for non-US listings the S&P 500 comparison leaves out currency moves.
How is Paul ranked on 13Foresight?
Paul Matteis is currently ranked #204 with a 5-star rating. Our rank blends hit rate, average return versus the market, and how many calls we have to judge — so a long, consistent record outweighs a few lucky picks. It is our own calculation, updated daily.
Which stocks does Paul cover?
Paul most recently has ratings on SION, VRTX, BMRN, DNLI, DFTX, XENE, GHRS, ACAD, IONS, BIIB, NBIX, DYN and 29 more. See the full coverage table above for positions, price targets and our measured returns.
Where can I see other analyst ratings?
Browse the full analyst leaderboard to compare Wall Street analysts ranked by their measured performance, success rate and average return.

Disclaimer: 13Foresight compiles analyst ratings and price targets from publicly available sources. Performance metrics, rankings and star ratings shown here are calculated independently by 13Foresight from historical market prices and may differ from figures published elsewhere. This information may be incomplete, delayed or inaccurate, is provided for research and informational purposes only, and is not investment advice. The underlying ratings and opinions are those of the respective analysts and their firms; 13Foresight accepts no liability for any decisions made based on this data.