Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Vertex Pharmaceuticals Inc (VRTX)

2K + Investors. Track Smart Money conviction in VRTX. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +38
Streak
2Q ▲
Buyers last Q
54%

Smart Money Signals — VRTX

Based on 1692 hedge funds · latest filing: 2026 Q1 · updated quarterly

📈

Buying streak — 2 quarters in a row

last 6Q
For 2 consecutive quarters, more hedge funds added VRTX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
1,692 hedge funds hold VRTX right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
📶

Steady growth — +7% more funds vs a year ago

fund count last 6Q
+108 new funds entered over the past year (+7% YoY). Gradual, steady growth in institutional ownership is generally a healthy signal — not a speculative rush, but consistent conviction.
🟡

Slight buying edge — 54% buying

858 buying732 selling
Last quarter: 858 funds bought or added vs 732 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.
⚠️

Fewer new buyers each quarter (-109 vs last Q)

new funds entering per quarter
Funds opening this position for the first time: 127 → 151 → 277 → 168. Each quarter fewer new institutions are entering. This usually means most funds that wanted in are already in — the stock is well-known but the pool of potential new buyers is shrinking.
🔒

65% of holders stayed for 2+ years

■ 65% conviction (2yr+) ■ 19% medium ■ 16% new
1,103 out of 1,692 hedge funds have held VRTX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
🚀

Acceleration phase — new buyers rushing in

210 → 127 → 151 → 277 → 168 new funds/Q
New funds entering each quarter: 127 → 151 → 277 → 168. The pace of institutional discovery is accelerating sharply. This is the 'hot idea' phase — the thesis is being passed from fund to fund. You are not late — the accumulation wave is still building.
🏛️

Veteran-anchored — 67% veterans vs 19% newcomers

■ 67% veterans ■ 14% 1-2yr ■ 19% new
Entry-cohort mix of 1,748 holders: 1,172 (67%) are 2+ year veterans, 236 entered 1–2 years ago, and 340 (19%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
🏆

Elite ownership — 61% AUM from top-100 funds

61% from top-100 AUM funds
70 of 1684 holders are among the 100 largest funds by AUM, controlling 61% of total institutional value in VRTX. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.
3.6
out of 10
Low Exit Risk
Exit risk score 3.6/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — VRTX

In 2026 Q1, 858 hedge funds were net buyers of VRTX (168 opened a new position, 690 added to an existing one), while 732 reduced or exited (602 trimmed, 130 sold completely) — a 54% buyer ratio, indicating a slight buying edge. Net buying has persisted for two consecutive quarters, a positive momentum signal. 61% of total institutional value in VRTX is held by top-100 AUM funds, reflecting elite-tier ownership quality. Net fund flow last quarter: +38 funds (more new holders than closures). Total institutional holders: 1692.

Hedge Fund Ownership: VRTX

How many hedge funds hold VRTX — quarterly history vs. share price
Quarterly hedge fund ownership of VRTX vs. share price

Market Analysis: VRTX

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: VRTX

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Is It Too Late to Buy Vertex Pharmaceuticals Inc (VRTX) Based on Hedge Fund 13F Filings?

Signal Freshness measures how much VRTX has moved relative to its sector benchmark (XLV) since the 2026 Q1 13F filing. A stock that has barely outrun its sector is still a relatively fresh entry point — the fund's thesis has not yet been priced in by the broader market.

Since Quarter End March 31, 2026 · 78d ago
VRTX
+2.5%
XLV
+3.7%

VRTX outperformed XLV by -1.2% since March 31, 2026.

Since 13F Filing Date May 15, 2026 · 33d ago
VRTX
+4.7%
XLV
+4.8%

Since the filing became public, VRTX outperformed XLV by -0.1% .

Interpretation: The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference. Learn more →

Smart Money Signal ?
Broad Consensus, Selective Conviction

Many quality funds hold this stock, but top-tier positions remain relatively small.

93 top-rated funds 16 high-conviction
Consensus
8.6
/ 10
breadth
×
Elite
4.8
/ 10
conviction
Hedge Fund Positioning: VRTX
2K + Investors

Track Smart Money conviction in VRTX. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q1) Prior (2025 Q4) Change
Funds Holding 1674 1654 1.21%
13F Shares 227M 238M -4.71%
Total Value $99.12B $106.53B -6.96%
New Positions 161 277 -116
Increased Positions 669 602 +67
Closed Positions 141 120 +21
Reduced Positions 585 568 +17
Total Calls 34 31 9.68%
Total Puts 30 31 -3.23%
PUT/CALL Ratio 0.88 1.0 Neutral

Statistics: VRTX

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Valuation Measures Data as of: --

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Enterprise Value/EBITDA --
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Short % of Float --

Financial Highlights

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Total Cash (mrq) --
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Institutional Holders (2026 Q1)

2K + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in VRTX. Verified SEC 13F-HR filings.

QUARTER:
Top 25 VRTX holders by conviction (% of portfolio weight) — 2026 Q1 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Jones Hill Capital LP 10.40% 108,603 $48.5M
2 Tri Locum Partners LP 8.10% 129,314 $57.7M
3 Bellevue Group AG 7.25% 681,908 $304.5M
4 Diadema Partners LP 7.07% 93,100 $41.6M
5 Provident Investment Management, Inc. 6.55% 147,620 $65.9M
6 Andrew Hill Investment Advisors, Inc. 4.76% 11,955 $5.3M
7 Eurizon SLJ Capital Ltd 4.54% 21,523 $9.5M
8 Atle Fund Management AB 3.61% 22,984 $11.2M
9 Superstring Capital Management LP 3.51% 11,010 $4.9M
10 Mcrae Capital Management Inc 3.16% 34,123 $15.2M
11 Nia Impact Advisors, LLC 3.08% 15,490 $6.9M
12 Birch Hill Investment Advisors LLC 3.02% 150,795 $67.3M
13 Sectoral Asset Management Inc 2.86% 7,007 $3.5M
14 Bender Robert & Associates 2.80% 26,171 $11.7M
15 AIMZ Investment Advisors, LLC 2.75% 19,956 $8.9M
16 Shelter Mutual Insurance Co 2.74% 27,600 $12.3M
17 Edgewood Management LLC 2.61% 905,129 $404.2M
18 Loomis Sayles & Co L P 2.41% 4,003,821 $1.79B
19 Rhenman & Partners Asset Management AB 2.40% 43,485 $19.4M
20 AlphaCentric Advisors LLC 2.20% 4,931 $2.2M
21 Motley Fool Wealth Management, LLC 2.16% 42,836 $19.1M
22 Private Harbour Investment Management & Counsel, LLC 2.15% 4,383 $2.0M
23 Mark Sheptoff Financial Planning, LLC 2.14% 9,546 $4.1M
24 Eversept Partners, LP 2.12% 90,000 $40.2M
25 B. Metzler seel. Sohn & Co. AG 2.12% 511,036 $228.2M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Vertex Pharmaceuticals Inc (VRTX)

What does the Smart Money Trend signal show for VRTX?

Buying streak — 2 quarters in a row: For 2 consecutive quarters, more hedge funds added VRTX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for VRTX?

Slight buying edge — 54% buying: Last quarter: 858 funds bought or added vs 732 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for VRTX holders?

Elite ownership — 61% AUM from top-100 funds: 70 of 1684 holders are among the 100 largest funds by AUM, controlling 61% of total institutional value in VRTX. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held VRTX?

65% of holders stayed for 2+ years: 1,103 out of 1,692 hedge funds have held VRTX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Is it too late to buy Vertex Pharmaceuticals Inc (VRTX) following the 2026 Q1 hedge fund 13F filings?

As of today, VRTX has moved +4.7% since the 2026 Q1 13F filing date (May 15, 2026), compared to +4.8% for the XLV sector ETF — an outperformance of -0.1%. Since the quarter end (March 31, 2026), VRTX has gained +2.5% vs +3.7% for XLV. The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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