Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

DENALI THERAPEUTICS INC (DNLI)

239 + Investors. Track Smart Money conviction in DNLI. See who's accumulating, reducing, or initiating positions.

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Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +15
Streak
3Q ▲
Buyers last Q
56%

Smart Money Signals — DNLI

Based on 234 hedge funds · latest filing: 2025 Q4 · updated quarterly

📈

Buying streak — 3 quarters in a row

last 6Q
For 3 consecutive quarters, more hedge funds added DNLI than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
234 hedge funds hold DNLI right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
📶

Steady growth — +11% more funds vs a year ago

fund count last 6Q
+24 new funds entered over the past year (+11% YoY). Gradual, steady growth in institutional ownership is generally a healthy signal — not a speculative rush, but consistent conviction.
🟡

Slight buying edge — 56% buying

134 buying106 selling
Last quarter: 134 funds bought or added vs 106 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.
📈

More new buyers each quarter (+20 vs last Q)

new funds entering per quarter
Funds opening a new DNLI position: 34 → 44 → 32 → 52. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔒

54% of holders stayed for 2+ years

54% conviction (2yr+) 22% medium 24% new
126 out of 234 hedge funds have held DNLI for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💎

Buying through price weakness — shares +7%, value -95%

Value
-95%
Shares
+7%
Last quarter: funds added +7% more shares while total portfolio value only changed -95%. Institutions were buying while the price was falling — a high-conviction accumulation signal. They're deliberately loading up on the dip.
➡️

Steady discovery — ~52 new funds/quarter

38 → 34 → 44 → 32 → 52 new funds/Q
New funds entering each quarter: 34 → 44 → 32 → 52. Consistent flow of new institutional buyers without clear acceleration or slowdown.
🏛️

Deep conviction — 58% of holders stayed 2+ years

58% veterans 13% 1-2yr 28% new
Of 239 current holders: 139 (58%) have held for over 2 years without selling. These are not momentum buyers — they have lived through drawdowns and stayed. A large veteran base acts as a stabilizing force during selloffs.
🏆

Elite ownership — 48% AUM from top-100 funds

48% from top-100 AUM funds
37 of 234 holders are among the 100 largest funds by AUM, controlling 48% of total institutional value in DNLI. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.
3.8
out of 10
Low Exit Risk
Exit risk score 3.8/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Hedge Fund Ownership: DNLI

How many hedge funds hold DNLI — quarterly history vs. share price
Quarterly hedge fund ownership of DNLI vs. share price

Market Analysis: DNLI

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: DNLI

-- --
Smart Money Signal ?
Broad Consensus, Selective Conviction

Many quality funds hold this stock, but top-tier positions remain relatively small.

41 top-rated funds 1 high-conviction
Consensus
7.0
/ 10
breadth
×
Elite
2.0
/ 10
conviction
Hedge Fund Positioning: DNLI
2026 Q1 Stats Unlock in 19 days 239 + Investors

Track Smart Money conviction in DNLI. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2025 Q4) Prior (2025 Q3) Change
Funds Holding 239 225 6.22%
13F Shares 145M 135M 7.21%
Total Value $2.33B $51.37B -95.47%
New Positions 53 34 +19
Increased Positions 84 91 -7
Closed Positions 39 28 +11
Reduced Positions 79 69 +10
Total Calls 4 4 -
Total Puts 1 2 -50.0%
PUT/CALL Ratio 0.25 0.5 Bullish

Statistics: DNLI

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Valuation Measures Data as of: --

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Enterprise Value --
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PEG Ratio (5yr expected) --
Price/Sales (ttm) --
Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

Profitability
Profit Margin --
Return on Assets (ttm) --
Return on Equity (ttm) --
Income Statement & Cash Flow
Revenue (ttm) --
Net Income Avi to Common (ttm) --
Diluted EPS (ttm) --
Total Cash (mrq) --
Total Debt/Equity (mrq) --
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Institutional Holders (2026 Q1)

239 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in DNLI. Verified SEC 13F-HR filings.

Top 25 institutional holders of DNLI — 2025 Q4 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 1492 Capital Management LLC 0.49% 67,417 $1.3M
2 Candriam S.C.A. 0.11% 1,099,845 $21.1M
3 China Universal Asset Management Co., Ltd. 0.06% 40,643 $780K
4 Aberdeen Group plc 0.06% 1,854,446 $35.6M
5 CONTRAVISORY INVESTMENT MANAGEMENT, INC. 0.06% 14,451 $277K
6 Pictet Asset Management Holding SA 0.05% 2,558,865 $48.4M
7 PROFUND ADVISORS LLC 0.05% 68,227 $1.3M
8 Breakwater Capital Group 0.04% 15,586 $299K
9 AlphaQuest LLC 0.04% 42,909 $708K
10 Y-Intercept (Hong Kong) Ltd 0.03% 78,007 $1.5M
11 SBI Okasan Asset Management Co.Ltd. 0.02% 29,500 $533K
12 B. Riley Wealth Advisors, Inc. 0.01% 12,213 $221K
13 NBC SECURITIES, INC. 0.01% 7,617 $146K
14 E Fund Management Co., Ltd. 0.01% 18,942 $364K
15 Police & Firemen's Retirement System of New Jersey 0.01% 38,545 $740K
16 SUMMIT SECURITIES GROUP LLC 0.01% 2,500 $48K
17 Handelsbanken Fonder AB 0.00% 43,800
18 Versant Capital Management, Inc 0.00% 1,476 $28K
19 Comprehensive Financial Planning, Inc./PA 0.00% 200 $4K
20 KLP KAPITALFORVALTNING AS 0.00% 30,900 $593K
21 Sterling Capital Management LLC 0.00% 4,493 $86K
22 Private Wealth Management Group, LLC 0.00% 296 $6K
23 Bayforest Capital Ltd 0.00% 67 $1K
24 TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% 17,882 $343K
25 GAMMA Investing LLC 0.00% 1,428 $27K
Investor Ownership
History
% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — DENALI THERAPEUTICS INC (DNLI)

What does the Smart Money Trend signal show for DNLI?

Buying streak — 3 quarters in a row: For 3 consecutive quarters, more hedge funds added DNLI than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for DNLI?

Slight buying edge — 56% buying: Last quarter: 134 funds bought or added vs 106 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for DNLI holders?

Elite ownership — 48% AUM from top-100 funds: 37 of 234 holders are among the 100 largest funds by AUM, controlling 48% of total institutional value in DNLI. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held DNLI?

54% of holders stayed for 2+ years: 126 out of 234 hedge funds have held DNLI for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.