2026 Q2 Portfolio Activity
In 2026 Q2, GREAT POINT PARTNERS LLC maintained a portfolio of 54 distinct positions. The most significant new addition was ABIVAX SA, now representing 10.07% of the total fund value. They heavily accumulated shares in VERA THERAPEUTICS INC, increasing the position by 201.4%. Conversely, GREAT POINT PARTNERS LLC completely exited their position in APOGEE THERAPEUTICS INC.
Position History
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Total Positions
54
Quarter
2026 Q2
Top Holding
ABVX (10.1%)
Top 10 Concentration
51.6%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-50 of 54
GREAT POINT PARTNERS LLC Full Holdings List — 2026 Q2
| Stock | History | Sector / Type | Port % | Prev % | Rank / Prev | Conviction | Change | % Change | Influence | Shares | Mkt Value | Avg Cost | Price Held | 1st Owned | Source | Source Date | Date Reported | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ABVX
CALL
ABIVAX SA
|
CALL Option | 10.07% | — |
#1
Prev: #—
|
9.5 |
—
|
400,000 | — |
NEW
|
400,000 | $53,304,000 | 2023 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
VOR
VOR BIOPHARMA I...
|
Healthcare | 5.91% | 7.18% |
#2
Prev: #2
|
4.4 |
—
|
-50,000 | -2.9% |
P
S
|
1,700,000 | $31,297,000 | 2025 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ABVX
ABIVAX SA
|
Healthcare | 5.15% | — |
#3
Prev: #—
|
6.6 |
—
|
204,314 | — |
NEW
|
204,314 | $27,226,884 | 2023 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
IBRX
PUT
IMMUNITYBIO INC
|
PUT Option | 4.97% | 5.29% |
#4
1
Prev: #5
|
3.5 |
—
|
no change | no change |
P
S
|
3,000,800 | $26,272,004 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
VERA
VERA THERAPEUTI...
|
Healthcare | 4.87% | 1.84% |
#5
16
Prev: #21
|
5.4 |
—
|
401,488 | 201.4% |
P
S
|
600,836 | $25,781,873 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ZURA
ZURA BIO LTD
|
Healthcare | 4.70% | 5.77% |
#6
3
Prev: #3
|
2.9 |
—
|
no change | no change |
P
S
|
4,215,930 | $24,873,987 | 2023 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ALMS
ALUMIS INC
|
Healthcare | 4.55% | 4.33% |
#7
1
Prev: #8
|
2.8 |
—
|
no change | no change |
P
S
|
856,061 | $24,089,557 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
SLGL
SOL-GEL TECHNOL...
|
Healthcare | 3.84% | 5.00% |
#8
1
Prev: #7
|
2.5 |
—
|
no change | no change |
P
S
|
274,363 | $20,341,273 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
RARE
PUT
ULTRAGENYX PHAR...
|
PUT Option | 3.79% | — |
#9
Prev: #—
|
5.0 |
—
|
600,000 | — |
NEW
|
600,000 | $20,034,000 | 2022 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
DFTX
DEFINIUM THERAP...
|
Healthcare | 3.78% | — |
#10
Prev: #—
|
5.0 |
—
|
425,000 | — |
NEW
|
425,000 | $19,992,000 | 2026 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ANNX
ANNEXON INC
|
Healthcare | 3.78% | 3.18% |
#11
1
Prev: #10
|
4.0 |
—
|
1,000,000 | 40.0% |
P
S
|
3,500,000 | $19,985,000 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ORKA
ORUKA THERAPEUT...
|
Healthcare | 3.30% | 2.07% |
#12
7
Prev: #19
|
2.3 |
—
|
no change | no change |
P
S
|
183,330 | $17,447,516 | 2024 Q3 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
MLTX
MOONLAKE IMMUNO...
|
Healthcare | 3.15% | 2.14% |
#13
4
Prev: #17
|
4.3 |
—
|
355,813 | 71.2% |
P
S
|
855,813 | $16,662,679 | 2022 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
SGMT
SAGIMET BIOSCIE...
|
Healthcare | 2.97% | — |
#14
Prev: #—
|
4.7 |
—
|
2,029,933 | — |
NEW
|
2,029,933 | $15,691,382 | 2026 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
CTNM
CONTINEUM THERA...
|
Healthcare | 2.85% | 2.40% |
#15
1
Prev: #14
|
3.1 |
—
|
121,283 | 15.2% |
P
S
|
921,481 | $15,103,074 | 2025 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
IMMX
IMMIX BIOPHARMA...
|
Healthcare | 2.49% | 0.73% |
#16
18
Prev: #34
|
4.0 |
—
|
927,642 | 265.0% |
P
S
|
1,277,642 | $13,172,489 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
CLYM
CLIMB BIO INC
|
Healthcare | 2.46% | 2.10% |
#17
1
Prev: #18
|
1.0 |
—
|
-334,130 | -25.0% |
P
S
|
1,000,000 | $13,040,000 | 2024 Q3 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
AMLX
AMYLYX PHARMACE...
|
Healthcare | 2.38% | 5.59% |
#18
14
Prev: #4
|
1.0 |
—
|
-1,050,000 | -60.0% |
P
S
|
700,000 | $12,572,000 | 2022 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
NKTR
NEKTAR THERAPEU...
|
Healthcare | 2.31% | 5.23% |
#19
13
Prev: #6
|
0.9 |
—
|
-141,453 | -44.7% |
P
S
|
175,000 | $12,216,750 | 2019 Q3 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
NGNE
NEUROGENE INC
|
Healthcare | 2.09% | 2.32% |
#20
4
Prev: #16
|
0.8 |
—
|
-147,820 | -29.6% |
P
S
|
352,180 | $11,076,061 | 2023 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
LBRX
LB PHARMACEUTIC...
|
Healthcare | 1.95% | 1.70% |
#21
2
Prev: #23
|
2.8 |
—
|
17,221 | 5.7% |
P
S
|
317,221 | $10,295,408 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
IRD
OPUS GENETICS I...
|
Healthcare | 1.53% | 0.34% |
#22
20
Prev: #42
|
3.6 |
—
|
1,645,847 | 507.4% |
P
S
|
1,970,187 | $8,097,469 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
EPRX
EUPRAXIA PHARMA...
|
Healthcare | 1.50% | 2.00% |
#23
3
Prev: #20
|
1.6 |
—
|
no change | no change |
P
S
|
1,200,000 | $7,932,000 | 2025 Q3 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
DRUG
BRIGHT MINDS BI...
|
Healthcare | 1.45% | 3.69% |
#24
15
Prev: #9
|
0.6 |
—
|
-110,397 | -50.2% |
P
S
|
109,603 | $7,694,131 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
IFRX
INFLARX NV
|
Healthcare | 1.29% | — |
#25
Prev: #—
|
4.0 |
—
|
3,046,557 | — |
NEW
|
3,046,557 | $6,824,288 | 2021 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
RLMD
RELMADA THERAPE...
|
Healthcare | 1.10% | 1.35% |
#26
2
Prev: #28
|
1.4 |
—
|
no change | no change |
P
S
|
842,106 | $5,827,374 | 2021 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
N/A
JATT II ACQUISI...
|
|
Unknown | 1.07% | — |
#27
Prev: #—
|
3.9 |
—
|
500,000 | — |
NEW
|
500,000 | $5,680,000 | — | 13F Filing | 2026-06-30 | 2026-08-14 | ||
|
CGEM
CULLINAN THERAP...
|
Healthcare | 1.03% | 0.98% |
#28
5
Prev: #33
|
1.4 |
—
|
no change | no change |
P
S
|
300,000 | $5,463,000 | 2025 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ALT
ALTIMMUNE INC
|
Healthcare | 1.00% | — |
#29
Prev: #—
|
3.9 |
—
|
1,741,232 | — |
NEW
|
1,741,232 | $5,293,345 | 2026 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
N/A
AMANAT ACQUISIT...
|
|
Unknown | 0.96% | — |
#30
Prev: #—
|
3.9 |
—
|
500,000 | — |
NEW
|
500,000 | $5,080,000 | — | 13F Filing | 2026-06-30 | 2026-08-14 | ||
|
RZLT
REZOLUTE INC
|
Healthcare | 0.94% | 0.67% |
#31
4
Prev: #35
|
1.4 |
—
|
no change | no change |
P
S
|
951,809 | $4,949,407 | 2024 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
SLN
SILENCE THERAPE...
|
Healthcare | 0.93% | 1.24% |
#32
3
Prev: #29
|
0.4 |
—
|
-570,489 | -55.9% |
P
S
|
450,000 | $4,941,000 | 2021 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
PALI
PALISADE BIO IN...
|
Healthcare | 0.90% | 1.37% |
#33
7
Prev: #26
|
0.4 |
—
|
-1,120,938 | -32.9% |
P
S
|
2,284,819 | $4,775,272 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
EVMN
EVOMMUNE INC
|
Healthcare | 0.82% | 1.72% |
#34
12
Prev: #22
|
1.3 |
—
|
no change | no change |
P
S
|
325,000 | $4,319,250 | 2025 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
SCYX
SCYNEXIS INC
|
Healthcare | 0.73% | 1.59% |
#35
10
Prev: #25
|
0.3 |
—
|
-6,610,055 | -87.5% |
P
S
|
944,292 | $3,843,268 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
GALT
CALL
GALECTIN THERAP...
|
CALL Option | 0.70% | 0.51% |
#36
2
Prev: #38
|
1.3 |
—
|
no change | no change |
P
S
|
800,000 | $3,712,000 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ELVN
ENLIVEN THERAPE...
|
Healthcare | 0.67% | — |
#37
Prev: #—
|
3.8 |
—
|
70,000 | — |
NEW
|
70,000 | $3,552,500 | 2026 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
HUMA
HUMACYTE INC
|
Healthcare | 0.55% | 0.52% |
#38
1
Prev: #37
|
1.2 |
—
|
no change | no change |
P
S
|
3,750,000 | $2,926,500 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
RNTX
REIN THERAPEUTI...
|
Healthcare | 0.51% | — |
#39
Prev: #—
|
3.7 |
—
|
2,575,000 | — |
NEW
|
2,575,000 | $2,678,000 | 2026 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
DBVT
DBV TECHNOLOGIE...
|
Healthcare | 0.49% | — |
#40
Prev: #—
|
3.7 |
—
|
156,906 | — |
NEW
|
156,906 | $2,573,258 | 2025 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
AVXL
CALL
ANAVEX LIFE SCI...
|
CALL Option | 0.26% | 0.37% |
#41
Prev: #41
|
1.1 |
—
|
no change | no change |
P
S
|
521,300 | $1,350,167 | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
PMN
PROMIS NEUROSCI...
|
Healthcare | 0.21% | 1.08% |
#42
10
Prev: #32
|
0.1 |
—
|
-285,252 | -76.8% |
P
S
|
86,150 | $1,133,734 | 2024 Q3 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ALKS
ALKERMES PLC
|
Healthcare | 0.00% | 0.41% |
Sold All 😨
(Was: #40) |
0.0 |
—
|
-50,000 | -100.0% |
CLOSED
|
— | $— | 2022 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
AVTX
AVALO THERAPEUT...
|
Healthcare | 0.00% | 0.43% |
Sold All 😨
(Was: #39) |
0.0 |
—
|
-124,666 | -100.0% |
CLOSED
|
— | $— | 2025 Q4 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
PHVS
PHARVARIS N V
|
Healthcare | 0.00% | 0.54% |
Sold All 😨
(Was: #36) |
0.0 |
—
|
-82,800 | -100.0% |
CLOSED
|
— | $— | 2025 Q3 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
TENX
TENAX THERAPEUT...
|
Healthcare | 0.00% | 1.20% |
Sold All 😨
(Was: #31) |
0.0 |
—
|
-327,307 | -100.0% |
CLOSED
|
— | $— | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
UNCY
UNICYCIVE THERA...
|
Healthcare | 0.00% | 1.20% |
Sold All 😨
(Was: #30) |
0.0 |
—
|
-796,558 | -100.0% |
CLOSED
|
— | $— | 2024 Q3 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
CNTX
CONTEXT THERAPE...
|
Healthcare | 0.00% | 1.35% |
Sold All 😨
(Was: #27) |
0.0 |
—
|
-2,238,496 | -100.0% |
CLOSED
|
— | $— | 2024 Q2 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
CMPX
COMPASS THERAPE...
|
Healthcare | 0.00% | 1.64% |
Sold All 😨
(Was: #24) |
0.0 |
—
|
-1,350,000 | -100.0% |
CLOSED
|
— | $— | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 | |||
|
ZBIO
ZENAS BIOPHARMA...
|
Healthcare | 0.00% | 2.35% |
Sold All 😨
(Was: #15) |
0.0 |
—
|
-524,066 | -100.0% |
CLOSED
|
— | $— | 2026 Q1 | 13F Filing | 2026-06-30 | 2026-08-14 |
Showing 1-50 of 54 holdings