AI Portfolio Summary
In 2025 Q4, Avidity Partners Management LP maintained a portfolio of 54 distinct positions. The most significant new addition to the portfolio was ALNYLAM PHARMACEUTIC, which now represents 2.41% of the total fund value. They heavily accumulated shares in JADE BIOSCIENCES INC, increasing their position by 24.3%. Conversely, Avidity Partners Management LP completely exited their position in IMMUNEERING CORP.
Total Positions
54
Quarter
2025 Q4
Top Holding
DNTH (25.0%)
Top 10 Concentration
71.9%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-50 of 54
| Stock | History | Sector / Type | Port % | Prev % | Rank / Prev | Conviction | Change | % Change | Influence | Shares | Mkt Value | Avg Cost | Price Held | 1st Owned | Source | Source Date | Date Reported |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
DNTH
DIANTHUS THERAP...
|
Healthcare | 25.01% | 28.70% |
#1
Prev: #1
|
6.0 | -1,100,000 | -34.3% |
P
S
|
2,104,184 | $86,713,423 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
CGON
CG ONCOLOGY INC
|
Healthcare | 17.64% | 14.68% |
#2
Prev: #2
|
6.0 | -128,200 | -8.0% |
P
S
|
1,472,699 | $61,146,462 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
JBIO
JADE BIOSCIENCE...
|
Healthcare | 6.23% | 2.21% |
#3
8
Prev: #11
|
6.0 | 273,522 | 24.3% |
P
S
|
1,400,708 | $21,612,924 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ORKA
ORUKA THERAPEUT...
|
Healthcare | 5.77% | 2.89% |
#4
1
Prev: #5
|
3.8 | no change | no change |
P
S
|
660,424 | $20,017,451 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
TEVA
TEVA PHARMACEUT...
|
Healthcare | 3.76% | 2.34% |
#5
4
Prev: #9
|
2.5 | -92,700 | -18.2% |
P
S
|
417,300 | $13,023,933 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
BSX
BOSTON SCIENTIF...
|
Healthcare | 3.15% | 3.65% |
#6
2
Prev: #4
|
1.3 | -49,800 | -30.3% |
P
S
|
114,500 | $10,917,575 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
MDT
MEDTRONIC PLC
|
Healthcare | 2.98% | 4.13% |
#7
4
Prev: #3
|
1.2 | -83,000 | -43.5% |
P
S
|
107,600 | $10,336,056 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
CATX
PERSPECTIVE THE...
|
Healthcare | 2.55% | 2.34% |
#8
2
Prev: #10
|
3.0 | 216,700 | 7.2% |
P
S
|
3,210,733 | $8,829,516 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ALNY
ALNYLAM PHARMAC...
|
Healthcare | 2.41% | — |
#9
Prev: #—
|
4.5 | 21,000 | no change |
NEW
|
21,000 | $8,350,650 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
RGEN
REPLIGEN CORP
|
Healthcare | 2.38% | 0.71% |
#10
21
Prev: #31
|
4.0 | 27,000 | 115.9% |
P
S
|
50,300 | $8,242,158 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
CNTX
CONTEXT THERAPE...
|
Healthcare | 2.33% | 1.98% |
#11
3
Prev: #14
|
0.9 | -3,477,000 | -38.7% |
P
S
|
5,504,855 | $8,092,137 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
MCK
MCKESSON CORP
|
Healthcare | 2.25% | 1.02% |
#12
12
Prev: #24
|
3.9 | 3,720 | 64.1% |
P
S
|
9,520 | $7,809,161 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ICLR
ICON PLC
|
Healthcare | 1.74% | — |
#13
Prev: #—
|
4.2 | 33,100 | no change |
NEW
|
33,100 | $6,031,482 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
A
AGILENT TECHNOL...
|
Healthcare | 1.63% | — |
#14
Prev: #—
|
4.2 | 41,500 | no change |
NEW
|
41,500 | $5,646,905 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
PFE
PFIZER INC
|
Healthcare | 1.46% | 2.12% |
#15
3
Prev: #12
|
0.6 | -162,800 | -44.4% |
P
S
|
203,600 | $5,069,640 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
CNC
CENTENE CORP DE...
|
Healthcare | 1.42% | — |
#16
Prev: #—
|
4.1 | 119,400 | no change |
NEW
|
119,400 | $4,913,310 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
KVUE
KENVUE INC
|
Consumer Defensive | 1.16% | 0.98% |
#17
9
Prev: #26
|
1.0 | -32,400 | -12.2% |
P
S
|
232,800 | $4,015,800 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
DHR
DANAHER CORPORA...
|
Healthcare | 1.12% | 2.47% |
#18
10
Prev: #8
|
0.4 | -37,700 | -68.9% |
P
S
|
17,000 | $3,891,640 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
TMO
THERMO FISHER S...
|
Healthcare | 1.12% | 2.09% |
#19
6
Prev: #13
|
0.4 | -12,200 | -64.6% |
P
S
|
6,700 | $3,882,315 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
NVO
NOVO-NORDISK A ...
|
Healthcare | 0.99% | — |
#20
Prev: #—
|
3.9 | 67,300 | no change |
NEW
|
67,300 | $3,424,224 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
PHAT
PHATHOM PHARMAC...
|
Healthcare | 0.99% | 0.82% |
#21
9
Prev: #30
|
0.4 | -99,924 | -32.7% |
P
S
|
206,076 | $3,418,801 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
EHC
ENCOMPASS HEALT...
|
Healthcare | 0.97% | 1.21% |
#22
2
Prev: #20
|
0.4 | -10,300 | -24.6% |
P
S
|
31,600 | $3,354,024 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
CI
THE CIGNA GROUP
|
Healthcare | 0.92% | 1.09% |
#23
1
Prev: #22
|
0.4 | -5,000 | -30.1% |
P
S
|
11,600 | $3,192,668 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
COR
CENCORA INC
|
Healthcare | 0.92% | 1.35% |
#24
5
Prev: #19
|
0.4 | -9,600 | -50.5% |
P
S
|
9,400 | $3,174,850 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
INSM
INSMED INC
|
Healthcare | 0.89% | 0.38% |
#25
16
Prev: #41
|
3.4 | 6,100 | 52.6% |
P
S
|
17,700 | $3,080,508 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
WAT
WATERS CORP
|
Healthcare | 0.89% | — |
#26
Prev: #—
|
3.9 | 8,100 | no change |
NEW
|
8,100 | $3,076,623 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ACAD
ACADIA PHARMACE...
|
Healthcare | 0.82% | 0.70% |
#27
5
Prev: #32
|
0.3 | -37,100 | -25.8% |
P
S
|
106,900 | $2,855,299 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
GMAB
GENMAB A/S
|
Healthcare | 0.82% | 1.73% |
#28
13
Prev: #15
|
0.3 | -156,100 | -62.9% |
P
S
|
92,000 | $2,833,600 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
NTRA
NATERA INC
|
Healthcare | 0.78% | 2.58% |
#29
22
Prev: #7
|
0.3 | -58,600 | -83.2% |
P
S
|
11,800 | $2,703,262 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
IMUX
IMMUNIC INC
|
Healthcare | 0.72% | 0.94% |
#30
3
Prev: #27
|
1.3 | no change | no change |
P
S
|
4,699,411 | $2,508,076 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ACHC
ACADIA HEALTHCA...
|
Healthcare | 0.69% | — |
#31
Prev: #—
|
3.8 | 169,000 | no change |
NEW
|
169,000 | $2,398,110 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ITGR
INTEGER HLDGS C...
|
Healthcare | 0.67% | — |
#32
Prev: #—
|
3.8 | 29,800 | no change |
NEW
|
29,800 | $2,337,214 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ELVN
ENLIVEN THERAPE...
|
Healthcare | 0.62% | 0.65% |
#33
1
Prev: #34
|
1.2 | no change | no change |
P
S
|
140,300 | $2,160,620 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
PVLA
PALVELLA THERAP...
|
Healthcare | 0.58% | — |
#34
Prev: #—
|
3.7 | 19,300 | no change |
NEW
|
19,300 | $2,020,131 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
HQY
HEALTHEQUITY IN...
|
Healthcare | 0.45% | 0.55% |
#35
2
Prev: #37
|
0.2 | -8,400 | -33.2% |
P
S
|
16,900 | $1,548,209 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
SCYX
SCYNEXIS INC
|
Healthcare | 0.38% | 0.59% |
#36
Prev: #36
|
0.2 | -1,268,868 | -37.9% |
P
S
|
2,081,660 | $1,316,442 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
IQV
IQVIA HLDGS INC
|
Healthcare | 0.29% | — |
#37
Prev: #—
|
3.6 | 4,400 | no change |
NEW
|
4,400 | $991,804 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
KPTI
KARYOPHARM THER...
|
Healthcare | 0.29% | 0.20% |
#38
4
Prev: #42
|
1.1 | no change | no change |
P
S
|
134,566 | $990,406 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
CORT
CORCEPT THERAPE...
|
Healthcare | 0.22% | — |
#39
Prev: #—
|
3.6 | 22,000 | no change |
NEW
|
22,000 | $765,600 | 2019 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
IMRX
IMMUNEERING COR...
|
Healthcare | 0.00% | 0.14% |
Sold All 😨
(Was: #43) |
0.0 | -90,900 | -100.0% |
CLOSED
|
— | $— | 2025 Q3 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
AKRO
AKERO THERAPEUT...
|
Healthcare | 0.00% | 0.44% |
Sold All 😨
(Was: #40) |
0.0 | -40,500 | -100.0% |
CLOSED
|
— | $— | 2022 Q3 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
XENE
XENON PHARMACEU...
|
Healthcare | 0.00% | 0.49% |
Sold All 😨
(Was: #39) |
0.0 | -53,400 | -100.0% |
CLOSED
|
— | $— | 2022 Q2 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
WVE
WAVE LIFE SCIEN...
|
Healthcare | 0.00% | 0.50% |
Sold All 😨
(Was: #38) |
0.0 | -297,500 | -100.0% |
CLOSED
|
— | $— | 2024 Q2 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
BEAM
BEAM THERAPEUTI...
|
Healthcare | 0.00% | 0.62% |
Sold All 😨
(Was: #35) |
0.0 | -112,000 | -100.0% |
CLOSED
|
— | $— | 2025 Q1 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ASND
ASCENDIS PHARMA...
|
Healthcare | 0.00% | 0.66% |
Sold All 😨
(Was: #33) |
0.0 | -14,500 | -100.0% |
CLOSED
|
— | $— | 2020 Q2 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
EXAS
EXACT SCIENCES ...
|
Healthcare | 0.00% | 0.92% |
Sold All 😨
(Was: #29) |
0.0 | -73,600 | -100.0% |
CLOSED
|
— | $— | 2020 Q4 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ARQT
ARCUTIS BIOTHER...
|
Healthcare | 0.00% | 0.92% |
Sold All 😨
(Was: #28) |
0.0 | -214,400 | -100.0% |
CLOSED
|
— | $— | 2022 Q3 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
CARL
CARLSMED INC
|
Healthcare | 0.00% | 0.98% |
Sold All 😨
(Was: #25) |
0.0 | -321,912 | -100.0% |
CLOSED
|
— | $— | 2025 Q3 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
ABBV
ABBVIE INC
|
Healthcare | 0.00% | 1.04% |
Sold All 😨
(Was: #23) |
0.0 | -19,800 | -100.0% |
CLOSED
|
— | $— | 2020 Q2 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) | |||
|
JNJ
JOHNSON & JOHNS...
|
Healthcare | 0.00% | 1.13% |
Sold All 😨
(Was: #21) |
0.0 | -26,800 | -100.0% |
CLOSED
|
— | $— | 2022 Q1 | 13F Filing | 2025-12-31 | 2026-02-14 (Est.) |
Showing 1-50 of 54 holdings