Stock Analysis

KARYOPHARM THERAPEUTICS INC COMMON STOCK USD (KPTI)

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Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +13
Streak
3Q ▲
Buyers last Q
70%

Smart Money Signals — KPTI

Based on 64 hedge funds · latest filing: 2025 Q4 · updated quarterly

📈

Buying streak — 3 quarters in a row

last 6Q
For 3 consecutive quarters, more hedge funds added this stock than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term trade.
🔻

Below peak — only 56% of 3.0Y high

56% of all-time peak
Only 64 funds hold this stock today versus a peak of 115 funds at 2023 Q2 — just 56% of the maximum. Low institutional ownership can mean the stock is out of favor, but it also means there's a large pool of potential buyers if sentiment turns.
📉

Outflows — 20% fewer funds vs a year ago

fund count last 6Q
16 fewer hedge funds hold this stock compared to a year ago (-20% decline). When institutions consistently reduce exposure, it's worth asking what they know that retail investors don't.
🟢

More buyers than sellers — 70% buying

42 buying18 selling
Last quarter: 42 funds were net buyers (23 opened a brand new position + 19 added to an existing one). Only 18 were sellers (8 trimmed + 10 sold completely). A clear majority buying is a strong confirmation signal.
📈

More new buyers each quarter (+16 vs last Q)

new funds entering per quarter
Funds opening this position for the first time: 4 → 10 → 7 → 23. A growing number of new institutional buyers means the stock is still being discovered — the opportunity hasn't been fully priced in.
🔒

66% of holders stayed for 2+ years

66% conviction (2yr+) 22% medium 12% new
42 out of 64 hedge funds have held this stock for over 2 years without selling. Long-term holders are harder to shake out during market dips — they represent a stable ownership base that reduces the risk of sudden mass selling.
💎

Buying through price weakness — shares +164%, value +27%

Value
+27%
Shares
+164%
Last quarter: funds added +164% more shares while total portfolio value only changed +27%. Institutions were buying while the price was falling — a high-conviction accumulation signal. They're deliberately loading up on the dip.
🚀

Acceleration phase — new buyers rushing in

11 → 4 → 10 → 7 → 23 new funds/Q
New funds entering each quarter: 4 → 10 → 7 → 23. The pace of institutional discovery is accelerating sharply. This is the 'hot idea' phase — the thesis is being passed from fund to fund. You are not late — the accumulation wave is still building.
🏛️

Deep conviction — 76% of holders stayed 2+ years

76% veterans 9% 1-2yr 16% new
Of 70 current holders: 53 (76%) have held for over 2 years without selling. These are not momentum buyers — they have lived through drawdowns and stayed. A large veteran base acts as a stabilizing force during selloffs.

Strong quality — 20% from major AUM funds

20% from top-100 AUM funds
13 of 64 current holders rank in the top 100 by AUM. A meaningful share of the ownership base comes from the most well-resourced institutions.
1.1
out of 10
Low Exit Risk
Exit risk score 1.1/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Hedge Fund Ownership: KPTI

How many hedge funds hold KPTI — quarterly history vs. share price
Quarterly hedge fund ownership of KPTI vs. share price

Market Analysis: KPTI

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Analyst Price Targets

-- Low
-- High
-- Average
-- Current

Analyst Recommendations

Stock Performance

Real-time

Company Profile: KPTI

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Hedge Fund Positioning: KPTI
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Metric All 13F Filers (2025 Q4) Prior (2025 Q3) Change

Statistics: KPTI

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Institutional Holders (2025 Q4)
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Investor Ownership
History
% of Portfolio Prev % Rank Conviction Avg Buy
Price
13F Score™ 3Y / 7Y Shares Mkt Value Change Change % Source Quarter Filed