Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Structure Therapeutics Inc (GPCR)

192 + Investors. Track Smart Money conviction in GPCR. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↓ -1
Streak
2Q ▼
Buyers last Q
56%

Smart Money Signals — GPCR

Based on 196 hedge funds · latest filing: 2026 Q2 · updated quarterly

📉

Selling streak — 2 quarters in a row

last 6Q
For 2 consecutive quarters, more hedge funds reduced or closed their GPCR positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.
🏔️

At the ownership peak (98% of max)

98% of all-time peak
196 hedge funds hold GPCR right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
📶

Steady growth — +13% more funds vs a year ago

fund count last 6Q
+23 new funds entered over the past year (+13% YoY). Gradual, steady growth in institutional ownership is generally a healthy signal — not a speculative rush, but consistent conviction.
🟡

Slight buying edge — 56% buying

111 buying86 selling
Last quarter: 111 funds bought or added vs 86 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.
⚠️

Fewer new buyers each quarter (-6 vs last Q)

new funds entering per quarter
Funds opening this position for the first time: 23 → 71 → 37 → 31. Each quarter fewer new institutions are entering. This usually means most funds that wanted in are already in — the stock is well-known but the pool of potential new buyers is shrinking.
📌

Mixed — 38% long-term, 30% new

■ 38% conviction (2yr+) ■ 32% medium ■ 30% new
Of the 196 current holders: 75 (38%) held >2 years, 63 held 1–2 years, and 58 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.
📊

Peak discovery — momentum slowing

37 → 23 → 71 → 37 → 31 new funds/Q
New funds entering each quarter: 23 → 71 → 37 → 31. GPCR is well-known in the hedge fund world, but fresh entries are gradually declining. The explosive phase of institutional discovery is likely behind us.
🏛️

Veteran-anchored — 41% veterans vs 37% newcomers

■ 41% veterans ■ 22% 1-2yr ■ 37% new
Entry-cohort mix of 202 holders: 82 (41%) are 2+ year veterans, 45 entered 1–2 years ago, and 75 (37%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
✅

Strong quality — 39% AUM from major funds

39% from top-100 AUM funds
38 of 192 holders rank in the top 100 by AUM, accounting for 39% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.
3.9
out of 10
Low Exit Risk
Exit risk score 3.9/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — GPCR

In 2026 Q2, 111 hedge funds were net buyers of GPCR (31 opened a new position, 80 added to an existing one), while 86 reduced or exited (54 trimmed, 32 sold completely) — a 56% buyer ratio, indicating a slight buying edge. Net selling has persisted for two consecutive quarters. 39% of total institutional value in GPCR is held by top-100 AUM funds, reflecting strong institutional quality. Net fund flow last quarter: -1 funds (more exits than new entries). Total institutional holders: 196.

Hedge Fund Ownership: GPCR

How many hedge funds hold GPCR — quarterly history vs. share price
Quarterly hedge fund ownership of GPCR vs. share price

Market Analysis: GPCR

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: GPCR

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Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Loading signal freshness…
Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

11 top-rated funds 7 high-conviction
Consensus
4.7
/ 10
breadth
×
Elite
4.6
/ 10
conviction
Hedge Fund Positioning: GPCR
192 + Investors

Track Smart Money conviction in GPCR. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q2) Prior (2026 Q1) Change
Funds Holding 192 197 -2.54%
13F Shares 68M 62M 9.52%
Total Value $3.60B $2.91B 23.94%
New Positions 31 37 -6
Increased Positions 76 72 +4
Closed Positions 32 39 -7
Reduced Positions 53 62 -9
Total Calls 7 6 16.67%
Total Puts 3 7 -57.14%
PUT/CALL Ratio 0.43 1.17 Bullish

Statistics: GPCR

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Institutional Holders (2026 Q2)

192 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in GPCR. Verified SEC 13F-HR filings.

QUARTER:
Top 25 GPCR holders by conviction (% of portfolio weight) — 2026 Q2 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 NEXTBio Capital Management LP 7.71% 312,496 $16.8M
2 Bvf Inc/Il 4.62% 3,366,823 $180.7M
3 Davern Capital Partners, LP 4.08% 446,059 $23.9M
4 Deep Track Capital, LP 3.70% 4,740,072 $254.4M
5 B Group, Inc. 3.53% 140,000 $7.5M
6 Avoro Capital Advisors LLC 3.16% 6,555,555 $351.8M
7 Casdin Capital, LLC 3.16% 1,175,000 $63.1M
8 Catalio Capital Management, LP 2.79% 276,550 $14.8M
9 Parkman Healthcare Partners LLC 2.67% 485,661 $26.1M
10 Orbimed Advisors LLC 2.20% 2,209,400 $118.6M
11 Rock Springs Capital Management LP 1.68% 640,317 $34.4M
12 HighVista Strategies LLC 1.60% 130,784 $7.0M
13 Flax Pond Capital, LLC 1.41% 37,000 $1.8M
14 Pacific Heights Asset Management LLC 1.36% 800,000 $42.9M
15 Buckland Partners Management Co LLC 1.31% 50,000 $2.7M
16 HSG Holding Ltd 1.19% 266,062 $14.3M
17 Platinum Investment Management Ltd 1.19% 90,363 $4.8M
18 Logos Global Management LP 1.16% 500,000 $26.8M
19 Siren, L.L.C. 0.95% 872,967 $46.9M
20 Avidity Partners Management LP 0.84% 98,000 $5.3M
21 Rtw Investments, LP 0.74% 1,607,507 $86.3M
22 Rhenman & Partners Asset Management AB 0.74% 145,100 $7.8M
23 PSquared Asset Management AG 0.65% 37,200 $2.0M
24 Deerfield Management Company, L.P. 0.61% 1,086,000 $58.3M
25 Birchview Capital, LP 0.60% 24,000 $1.3M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Structure Therapeutics Inc (GPCR)

What does the Smart Money Trend signal show for GPCR?

Selling streak — 2 quarters in a row: For 2 consecutive quarters, more hedge funds reduced or closed their GPCR positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.

What is the institutional breadth score for GPCR?

Slight buying edge — 56% buying: Last quarter: 111 funds bought or added vs 86 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for GPCR holders?

Strong quality — 39% AUM from major funds: 38 of 192 holders rank in the top 100 by AUM, accounting for 39% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.

How long have hedge funds held GPCR?

Mixed — 38% long-term, 30% new: Of the 196 current holders: 75 (38%) held >2 years, 63 held 1–2 years, and 58 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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