Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Structure Therapeutics Inc (GPCR)

197 + Investors. Track Smart Money conviction in GPCR. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↓ -2
Streak
1Q ▼
Buyers last Q
51%

Smart Money Signals — GPCR

Based on 197 hedge funds · latest filing: 2026 Q1 · updated quarterly

📉

Selling streak — 1 quarter in a row

last 6Q
For 1 consecutive quarter, more hedge funds reduced or closed their GPCR positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.
🏔️

At the ownership peak (99% of max)

99% of all-time peak
197 hedge funds hold GPCR right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
🚀

Fast accumulation — +30% more funds vs a year ago

fund count last 6Q
+45 new funds entered over the past year (+30% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.
🟡

Slight buying edge — 51% buying

111 buying106 selling
Last quarter: 111 funds bought or added vs 106 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.
⚠️

Fewer new buyers each quarter (-34 vs last Q)

new funds entering per quarter
Funds opening this position for the first time: 36 → 23 → 71 → 37. Each quarter fewer new institutions are entering. This usually means most funds that wanted in are already in — the stock is well-known but the pool of potential new buyers is shrinking.
📌

Mixed — 34% long-term, 35% new

■ 34% conviction (2yr+) ■ 31% medium ■ 35% new
Of the 197 current holders: 67 (34%) held >2 years, 62 held 1–2 years, and 68 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.
💎

Buying through price weakness — shares -8%, value -37%

Value
-36%
Shares
-8%
Last quarter: funds added -8% more shares while total portfolio value only changed -37%. Institutions were buying while the price was falling — a high-conviction accumulation signal. They're deliberately loading up on the dip.
🚀

Acceleration phase — new buyers rushing in

23 → 36 → 23 → 71 → 37 new funds/Q
New funds entering each quarter: 36 → 23 → 71 → 37. The pace of institutional discovery is accelerating sharply. This is the 'hot idea' phase — the thesis is being passed from fund to fund. You are not late — the accumulation wave is still building.
📊

Mixed cohorts — 37% veterans, 39% new entrants

■ 37% veterans ■ 24% 1-2yr ■ 39% new
Of 207 current holders: 76 (37%) held 2+ years, 50 held 1–2 years, 81 (39%) entered in the past year. Balanced distribution — some institutional memory, some recent momentum buyers.
🏆

Elite ownership — 42% AUM from top-100 funds

42% from top-100 AUM funds
32 of 194 holders are among the 100 largest funds by AUM, controlling 42% of total institutional value in GPCR. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.
4.3
out of 10
Moderate Exit Risk
Exit risk score 4.3/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — GPCR

In 2026 Q1, 111 hedge funds were net buyers of GPCR (37 opened a new position, 74 added to an existing one), while 106 reduced or exited (67 trimmed, 39 sold completely) — a 51% buyer ratio, indicating a slight buying edge. 42% of total institutional value in GPCR is held by top-100 AUM funds, reflecting elite-tier ownership quality. Net fund flow last quarter: -2 funds (more exits than new entries). Total institutional holders: 197.

Hedge Fund Ownership: GPCR

How many hedge funds hold GPCR — quarterly history vs. share price
Quarterly hedge fund ownership of GPCR vs. share price

Market Analysis: GPCR

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: GPCR

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Is It Too Late to Buy Structure Therapeutics Inc (GPCR) Based on Hedge Fund 13F Filings?

Signal Freshness measures how much GPCR has moved relative to its sector benchmark (XLV) since the 2026 Q1 13F filing. A stock that has barely outrun its sector is still a relatively fresh entry point — the fund's thesis has not yet been priced in by the broader market.

Since Quarter End March 31, 2026 · 79d ago
GPCR
-6.6%
XLV
+2.8%

GPCR outperformed XLV by -9.4% since March 31, 2026.

Since 13F Filing Date May 15, 2026 · 34d ago
GPCR
+16.3%
XLV
+3.9%

Since the filing became public, GPCR outperformed XLV by +12.4% .

Interpretation: The stock has meaningfully outrun its sector. The trade has partially played out; entry is at a premium to the fund's implied reference. Learn more →

Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

13 top-rated funds 4 high-conviction
Consensus
5.0
/ 10
breadth
×
Elite
4.0
/ 10
conviction
Hedge Fund Positioning: GPCR
197 + Investors

Track Smart Money conviction in GPCR. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q1) Prior (2025 Q4) Change
Funds Holding 197 199 -1.01%
13F Shares 62M 68M -8.13%
Total Value $2.91B $4.60B -36.77%
New Positions 37 71 -34
Increased Positions 72 54 +18
Closed Positions 39 30 +9
Reduced Positions 62 62 -
Total Calls 6 8 -25.0%
Total Puts 7 5 40.0%
PUT/CALL Ratio 1.17 0.62 Neutral

Statistics: GPCR

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Financial Highlights

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Institutional Holders (2026 Q1)

197 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in GPCR. Verified SEC 13F-HR filings.

QUARTER:
Top 25 GPCR holders by conviction (% of portfolio weight) — 2026 Q1 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Bvf Inc/Il 5.31% 3,459,358 $166.7M
2 B Group, Inc. 4.56% 127,500 $6.1M
3 Casdin Capital, LLC 4.29% 1,175,000 $56.6M
4 Deep Track Capital, LP 3.37% 4,279,848 $206.3M
5 Avoro Capital Advisors LLC 3.11% 6,555,555 $316.0M
6 NEXTBio Capital Management LP 2.98% 133,239 $6.4M
7 Birchview Capital, LP 2.74% 100,000 $4.8M
8 Catalio Capital Management, LP 2.57% 255,379 $12.3M
9 Stempoint Capital LP 1.88% 200,267 $9.7M
10 Rock Springs Capital Management LP 1.82% 640,217 $30.9M
11 Siren, L.L.C. 1.78% 1,328,698 $64.0M
12 Davern Capital Partners, LP 1.67% 126,461 $6.1M
13 HighVista Strategies LLC 1.65% 123,909 $6.0M
14 Buckland Partners Management Co LLC 1.46% 50,000 $2.4M
15 Sio Capital Management, LLC 1.45% 209,093 $10.1M
16 Orbimed Advisors LLC 1.41% 1,475,403 $71.1M
17 Flax Pond Capital, LLC 1.40% 36,000 $1.7M
18 Monashee Investment Management LLC 1.31% 50,000 $2.4M
19 Pacific Heights Asset Management LLC 1.21% 750,000 $36.1M
20 Logos Global Management LP 1.20% 500,000 $24.1M
21 Parkman Healthcare Partners LLC 1.15% 232,093 $11.2M
22 Diadema Partners LP 1.05% 127,500 $6.1M
23 Jones Hill Capital LP 1.04% 100,593 $4.8M
24 Platinum Investment Management Ltd 0.81% 66,864 $3.2M
25 Rhenman & Partners Asset Management AB 0.76% 128,100 $6.2M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Structure Therapeutics Inc (GPCR)

What does the Smart Money Trend signal show for GPCR?

Selling streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds reduced or closed their GPCR positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.

What is the institutional breadth score for GPCR?

Slight buying edge — 51% buying: Last quarter: 111 funds bought or added vs 106 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for GPCR holders?

Elite ownership — 42% AUM from top-100 funds: 32 of 194 holders are among the 100 largest funds by AUM, controlling 42% of total institutional value in GPCR. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held GPCR?

Mixed — 34% long-term, 35% new: Of the 197 current holders: 67 (34%) held >2 years, 62 held 1–2 years, and 68 entered in the last year. A mixed base — the stock has long-term believers but also recent buyers who haven't been tested by a downturn yet.

Is it too late to buy Structure Therapeutics Inc (GPCR) following the 2026 Q1 hedge fund 13F filings?

As of today, GPCR has moved +16.3% since the 2026 Q1 13F filing date (May 15, 2026), compared to +3.9% for the XLV sector ETF — an outperformance of +12.4%. Since the quarter end (March 31, 2026), GPCR has gained -6.6% vs +2.8% for XLV. The stock has meaningfully outrun its sector. The trade has partially played out; entry is at a premium to the fund's implied reference.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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