RYTM — Rhythm Pharmaceuticals Inc

Ownership history in Siren, L.L.C.  ·  4 quarters on record

This page tracks every 13F SEC filing in which Siren, L.L.C. reported a position in Rhythm Pharmaceuticals Inc (RYTM). Data includes quarterly share count, position size as % of portfolio, estimated market value, and end-of-quarter stock price — sourced directly from SEC EDGAR 13F filings.

Peak position
1.98% (2025 Q3)
Avg. % of fund
1.44%
First filed
2025 Q1
Last filed
2025 Q4
Quarters held
4
Quarter Action Shares Change Chg % % of Fund Mkt Value Price (EOQ)
2025 Q4 UNCHANGED 499,975 — 0% 1.60% $53.5M $107.04
2025 Q3 ADDED 499,975 +90,233 +22.0% 1.98% $50.5M $100.99
2025 Q2 ADDED 409,742 +132,209 +47.6% 1.34% $25.9M $63.19
2025 Q1 INITIATED 277,533 — — 0.84% $14.7M $52.97
% of Fund (quarterly)    RYTM price (monthly, adj. close)

Other funds also holding RYTM

As of 2025 Q4 — sorted by position size

Checkpoint Capital L.P. 33.18% NEA Management Company, LLC 3Y 7Y 15.88% RA CAPITAL MANAGEMENT, L.P. 3Y 7Y 7.31% PERCEPTIVE ADVISORS LLC 3Y 7Y 4.86% Nan Fung Group Holdings Ltd 3Y 4.71% Opaleye Management Inc. 3Y 7Y 4.66% Sio Capital Management, LLC 3Y 7Y 4.47% Rock Springs Capital Management LP 3Y 7Y 3.81% BAKER BROS. ADVISORS LP 3Y 7Y 3.51% Integral Health Asset Management, LLC 3Y 2.52%
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