SIMPLEX TRADING, LLC KPTI — KARYOPHARM THERAPEUTICS INC

Ownership history in SIMPLEX TRADING, LLC  ·  30 quarters on record

AI Ownership Summary

SIMPLEX TRADING, LLC reported KARYOPHARM THERAPEUTICS INC (KPTI) in 30 quarterly 13F filings from 2025 Q2 through 2026 Q3. The latest visible filing shows KPTI at 0.00% of the fund.

This page tracks quarterly shares, estimated market value, portfolio weight, filing dates, and disclosure-aligned stock prices directly from SEC EDGAR 13F filings. Older history is available after unlock; the visible window still shows the most recent pattern.

What this KPTI ownership page tells you

This page is designed to answer the real investor question behind a 13F filing: how meaningful was SIMPLEX TRADING, LLC's position in KARYOPHARM THERAPEUTICS INC, and how did that conviction change over time? You can read the holding window, peak weight, latest reported size, disclosure timing, and quarter-by-quarter changes without piecing the story together from raw SEC rows.

Freshest filing
Latest Reported Filing
2026 Q3

KPTI was reported at 0.00% of portfolio in the most recent visible filing.

High-water mark
Peak Conviction
0.0% in 2026 Q2

Peak weight helps separate a token disclosure from a real conviction holding the fund genuinely cared about.

Time in book
Holding Window
2025 Q2 to 2026 Q3

Longer holding windows often tell a very different story from short-lived tactical trades or one-quarter experiments.

Decision context
Why It Matters
Position size beats headlines

Knowing that a fund owned a stock is useful. Knowing whether it was a 0.20% placeholder or a true high-conviction position is where the signal actually starts.

KPTI stock page SIMPLEX TRADING, LLC fund profile SIMPLEX TRADING, LLC full holdings
How SIMPLEX TRADING, LLC held KPTI — position size vs. price
% of Fund (quarterly)    KPTI price (quarter-end, indexed to 100)    SPY (indexed to 100)    QQQ (indexed to 100)
📋 Quarterly Holdings History 5 quarters  ▾
Quarter Action Sold % After 3M Timing Shares Change Chg % % of Fund Mkt Value Filed Price (Filed)
2026 Q3 ADDED — — — 69,837 +45,751 +189.9% 0.00% $85K 2026-11-04 $0.07
2026 Q2 REDUCED 26.7% -83.4% ✅ 24,086 -8,782 -26.7% 0.00% $235K 2026-08-12 $2.03
2025 Q4 ADDED — — — 32,868 +27,006 +460.7% 0.00% $242K 2026-02-11 $7.37
2025 Q3 REDUCED 28.8% +12.2% ❌ 5,862 -2,371 -28.8% 0.00% $38K 2025-11-12 $5.59
2025 Q2 REDUCED 85.3% +47.3% ❌ 8,233 -47,752 -85.3% 0.00% $35K 2025-08-05 $3.88
25 older quarters hidden  —  Sign in free or upgrade to Premium to see full history

🏢 Other funds also holding KPTI

As of 2026 Q3 — sorted by position size

Context Capital Management, LLC 3Y 7Y 0.01% STRS OHIO 3Y 7Y 0.0% China Universal Asset Management Co., Ltd. 3Y 0.0% StoneX Group Inc. 3Y 7Y 0.0% Owl Creek Wealth Partners LLC 0.0% MB, LEVIS & ASSOCIATES, LLC 0.0% GAMMA Investing LLC 0.0% Caitong International Asset Management Co., Ltd 0.0% CITIGROUP INC 3Y 7Y 0.0% Activest Wealth Management 3Y 0.0%

FAQ About SIMPLEX TRADING, LLC and KPTI

These are the practical questions this page is built to answer before you even open the full history table.

How long has SIMPLEX TRADING, LLC reported owning KPTI?

SIMPLEX TRADING, LLC reported KPTI across 5 quarterly 13F filings, from 2025 Q2 through 2026 Q3.

What was the largest reported KPTI position in SIMPLEX TRADING, LLC's portfolio?

The largest reported portfolio weight for KPTI was 0.00% in 2026 Q2.

What is the latest reported KPTI position on this page?

The most recent filing on this page is 2026 Q3, when SIMPLEX TRADING, LLC reported 69,837 shares, equal to 0.00% of portfolio, with an estimated market value of $85K.

What does the chart on this KPTI ownership page compare?

The chart compares SIMPLEX TRADING, LLC's quarterly KPTI portfolio weight with the stock's indexed share price, so you can see whether the fund was building, trimming, or holding the position as price moved.

How well did SIMPLEX TRADING, LLC time their KPTI position?

Based on 13F filing dates vs. subsequent KPTI price moves, SIMPLEX TRADING, LLC correctly timed 10 out of 29 reported position changes (34%). The annualised alpha on KPTI relative to SPY over the holding period was -59.7%.

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