Samsara BioCapital, LLC ZYME — ZYMEWORKS INC

Ownership history in Samsara BioCapital, LLC  ·  11 quarters on record

AI Ownership Summary

Samsara BioCapital, LLC reported ZYMEWORKS INC (ZYME) in 11 quarterly 13F filings from 2023 Q4 through 2025 Q3. Peak portfolio weight reached 2.41% in 2024 Q3. The latest visible filing shows ZYME at 0.46% of the fund.

This page tracks quarterly shares, estimated market value, portfolio weight, filing dates, and disclosure-aligned stock prices directly from SEC EDGAR 13F filings. Older history is available after unlock; the visible window still shows the most recent pattern.

What this ZYME ownership page tells you

This page is designed to answer the real investor question behind a 13F filing: how meaningful was Samsara BioCapital, LLC's position in ZYMEWORKS INC, and how did that conviction change over time? You can read the holding window, peak weight, latest reported size, disclosure timing, and quarter-by-quarter changes without piecing the story together from raw SEC rows.

Freshest filing
Latest Reported Filing
2025 Q3

ZYME was reported at 0.46% of portfolio in the most recent visible filing.

High-water mark
Peak Conviction
2.41% in 2024 Q3

Peak weight helps separate a token disclosure from a real conviction holding the fund genuinely cared about.

Time in book
Holding Window
2023 Q4 to 2025 Q3

Longer holding windows often tell a very different story from short-lived tactical trades or one-quarter experiments.

Decision context
Why It Matters
Position size beats headlines

Knowing that a fund owned a stock is useful. Knowing whether it was a 0.20% placeholder or a true high-conviction position is where the signal actually starts.

ZYME stock page Samsara BioCapital, LLC fund profile Samsara BioCapital, LLC full holdings
How Samsara BioCapital, LLC held ZYME — position size vs. price
% of Fund (quarterly)    ZYME price (quarter-end, indexed to 100)    SPY (indexed to 100)    QQQ (indexed to 100)
📋 Quarterly Holdings History 8 quarters  ▾
Quarter Action Sold % After 3M Timing Shares Change Chg % % of Fund Mkt Value Filed Price (Filed)
2025 Q3 REDUCED 33.0% +56.6% ❌ 207,901 -102,399 -33.0% 0.46% $3.6M 2025-11-14 $18.52
2025 Q2 REDUCED 53.5% +37.3% ❌ 310,300 -356,367 -53.5% 0.80% $3.9M 2025-08-14 $14.30
2025 Q1 REDUCED 33.3% +5.4% ❌ 666,667 -333,333 -33.3% 1.42% $7.9M 2025-05-15 $11.53
2024 Q4 UNCHANGED — — — 1,000,000 — 0% 2.01% $14.6M 2025-02-14 $15.01
2024 Q3 UNCHANGED — — — 1,000,000 — 0% 2.41% $12.6M 2024-11-14 $16.26
2024 Q2 REDUCED 31.5% +47.5% ❌ 1,000,000 -458,875 -31.5% 1.78% $8.5M 2024-08-14 $10.14
2024 Q1 UNCHANGED — — — 1,458,875 — 0% 2.37% $15.3M 2024-05-15 $9.15
2023 Q4 UNCHANGED — — — 1,458,875 — 0% 2.36% $15.2M 2024-02-14 $11.41
3 older quarters hidden  —  Sign in free or upgrade to Premium to see full history

🏢 Other funds also holding ZYME

As of 2026 Q1 — sorted by position size

EcoR1 Capital, LLC 3Y 7Y 24.41% Capricorn Fund Managers Ltd 3Y 3.93% BVF INC/IL 3Y 7Y 2.98% Verdad Advisers, LP 3Y 2.33% Prosight Management, LP 3Y 7Y 2.21% Nextech Invest, Ltd. 1.96% Rubric Capital Management LP 3Y 7Y 1.86% PERCEPTIVE ADVISORS LLC 3Y 7Y 1.72% MPM BioImpact LLC 3Y 1.09% Redmile Group, LLC 3Y 7Y 0.82%

FAQ About Samsara BioCapital, LLC and ZYME

These are the practical questions this page is built to answer before you even open the full history table.

How long has Samsara BioCapital, LLC reported owning ZYME?

Samsara BioCapital, LLC reported ZYME across 8 quarterly 13F filings, from 2023 Q4 through 2025 Q3.

What was the largest reported ZYME position in Samsara BioCapital, LLC's portfolio?

The largest reported portfolio weight for ZYME was 2.41% in 2024 Q3.

What is the latest reported ZYME position on this page?

The most recent filing on this page is 2025 Q3, when Samsara BioCapital, LLC reported 207,901 shares, equal to 0.46% of portfolio, with an estimated market value of $3.6M.

What does the chart on this ZYME ownership page compare?

The chart compares Samsara BioCapital, LLC's quarterly ZYME portfolio weight with the stock's indexed share price, so you can see whether the fund was building, trimming, or holding the position as price moved.

How well did Samsara BioCapital, LLC time their ZYME position?

Based on 13F filing dates vs. subsequent ZYME price moves, Samsara BioCapital, LLC correctly timed 0 out of 5 reported position changes (0%). The annualised alpha on ZYME relative to SPY over the holding period was +4.7%.

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