Omega Fund Management, LLC

All Holdings — 2025 Q4

AI Portfolio Summary
In 2025 Q4, Omega Fund Management, LLC maintained a portfolio of 12 distinct positions. They heavily accumulated shares in enGene Holdings Inc., increasing their position by 66.5%. Conversely, Omega Fund Management, LLC completely exited their position in enGene Holdings Inc..
PCA Score Concentration Risk
Risk ENB
Total Positions
12
Quarter
2025 Q4
Top Holding
NUVB (25.3%)
Top 10 Concentration
99.2%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
1-12 of 12
Stock History Sector / Type Port % Prev % Rank / Prev Conviction Change % Change Influence Shares Mkt Value Avg Cost Price Held 1st Owned Source Source Date Date Reported
NUVB
Nuvation Bio
Healthcare 25.27% 14.69% #1 4
Prev: #5
6.5 -750,000 -8.5%
P
S
8,081,089 $72,406,557 2021 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
BBOT
BridgeBio Oncol...
Healthcare 14.37% 17.13% #2 1
Prev: #3
6.5 no change no change
P
S
3,289,661 $41,186,556 2025 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
BBNX
Beta Bionics In...
Healthcare 14.00% 17.16% #3 1
Prev: #2
5.0 -603,942 -31.5%
P
S
1,316,183 $40,104,096 2025 Q1 13F Filing 2025-12-31 2026-02-14 (Est.)
BCAX
Bicara Therapeu...
Healthcare 12.95% 15.66% #4
Prev: #4
5.5 no change no change
P
S
2,204,650 $37,104,260 2024 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
KMTS
Kestra Med Tech...
Healthcare 12.71% 17.59% #5 4
Prev: #1
5.0 -272,302 -16.5%
P
S
1,373,591 $36,427,633 2025 Q1 13F Filing 2025-12-31 2026-02-14 (Est.)
UPB
Upstream Bio In...
Healthcare 12.57% 11.47% #6
Prev: #6
4.5 -30,000 -2.2%
P
S
1,326,293 $36,008,855 2025 Q1 13F Filing 2025-12-31 2026-02-14 (Est.)
ENGN
enGene Holdings...
Healthcare 2.76% 1.62% #7 1
Prev: #8
4.1 350,000 66.5%
P
S
876,357 $7,913,504 2023 Q4 13F Filing 2025-12-31 2026-02-14 (Est.)
ALMS
Alumis Inc.
Healthcare 2.23% 1.17% #8 2
Prev: #10
1.9 no change no change
P
S
653,223 $6,375,456 2024 Q2 13F Filing 2025-12-31 2026-02-14 (Est.)
SANA
Sana Biotechnol...
Healthcare 1.20% 1.35% #9
Prev: #9
1.5 no change no change
P
S
843,750 $3,434,063 2021 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
IMA
ImageneBio, Inc...
Healthcare 1.10% 1.67% #10 3
Prev: #7
1.4 no change no change
P
S
455,361 $3,141,991 2025 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
REPL
Replimune Group
Healthcare 0.84% 0.47% #11
Prev: #11
1.3 no change no change
P
S
248,672 $2,417,092 2018 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
ENGNW
enGene Holdings...
Bond/Debt 0.00% 0.03%
Sold All 😨
(Was: #12)
0.0 -89,702 -100.0%
CLOSED
$— 2023 Q4 13F Filing 2025-12-31 2026-02-14 (Est.)
Showing 1-12 of 12 holdings

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