New Leaf Venture Partners, L.L.C. — 13F Holdings

2025 Q3  ·  8 Positions

2025 Q3 Portfolio Activity

In 2025 Q3, New Leaf Venture Partners, L.L.C. maintained a portfolio of 8 distinct positions. The fund also reduced its exposure to PASSAGE BIO by 96.5%.
Position History hover any row below to update
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New Leaf Venture Partners, L.L.C. New York, NY Venture Capital / Life Sciences AUM $43M
Fund Overview SEC EDGAR
PCA Score Concentration Risk
Risk ENB
To Excel To CSV
Total Positions
8
Quarter
2025 Q3
Top Holding
EWTX (38.8%)
Top 10 Concentration
100.0%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-8 of 8
Stock History Sector / Type Port % Prev % Rank / Prev Conviction
Freshness
Change % Change Influence Shares Mkt Value Avg Cost Price Held 1st Owned Source Source Date Date Reported
EWTX
EWTX
Healthcare 38.82% 25.51% #1 1
Prev: #2
7.0
—
no change no change
P
S
1,030,161 $16,709,211 2021 Q1 13F Filing 2025-09-30 2025-11-14 (Est.)
ARVN
ARVN
Healthcare 31.38% 22.04% #2 1
Prev: #3
6.5
—
no change no change
P
S
1,585,721 $13,510,343 2018 Q3 13F Filing 2025-09-30 2025-11-14 (Est.)
CRNX
CRNX
Healthcare 13.64% 7.66% #3 1
Prev: #4
6.0
—
no change no change
P
S
141,000 $5,872,650 2018 Q3 13F Filing 2025-09-30 2025-11-14 (Est.)
COGT
COGT
Bond/Debt 8.37% 3.40% #4 1
Prev: #5
4.8
—
no change no change
P
S
250,765 $3,600,985 2020 Q4 13F Filing 2025-09-30 2025-11-14 (Est.)
RLYB
RLYB
Healthcare 3.83% 2.11% #5 1
Prev: #6
3.0
—
no change no change
P
S
3,301,603 $1,647,500 2021 Q3 13F Filing 2025-09-30 2025-11-14 (Est.)
ALEC
ALEC
Healthcare 2.33% 0.90% #6 1
Prev: #7
1.9
—
no change no change
P
S
339,569 $1,005,124 2019 Q1 13F Filing 2025-09-30 2025-11-14 (Est.)
PASG
PASG
Healthcare 1.63% 37.74% #7 6
Prev: #1
0.7
—
-2,410,496 -96.5%
P
S
87,426 $702,031 2020 Q1 13F Filing 2025-09-30 2025-11-14 (Est.)
ITRM
ITERUM THERAPEU...
Healthcare 0.00% 0.65%
Sold All 😨
(Was: #8)
 0.0
—
-345,020 -100.0%
CLOSED
 — $— 2022 Q4 13F Filing 2025-09-30 2025-11-14 (Est.)
Showing 1-8 of 8 holdings

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