Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

TWIST BIOSCIENCE CORP (TWST)

236 + Investors. Track Smart Money conviction in TWST. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +12
Streak
1Q ▲
Buyers last Q
52%

Smart Money Signals — TWST

Based on 231 hedge funds · latest filing: 2025 Q4 · updated quarterly

📈

Buying streak — 1 quarter in a row

last 6Q
For 1 consecutive quarter, more hedge funds added TWST than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
📊

High ownership — 92% of 3.0Y peak

92% of all-time peak
231 funds currently hold this stock — 92% of the 3.0-year high of 250 funds (reached 2024 Q2). Ownership is elevated but not yet at maximum concentration. Room to grow, but watch if the trend reverses.
〰️

Stable — ownership unchanged year-over-year

fund count last 6Q
The number of hedge funds holding TWST is almost the same as a year ago (-4 funds, -2% change). No significant rush to buy or sell — institutional backing is holding steady.
🟡

Slight buying edge — 52% buying

123 buying115 selling
Last quarter: 123 funds bought or added vs 115 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.
📈

More new buyers each quarter (+20 vs last Q)

new funds entering per quarter
Funds opening a new TWST position: 45 → 35 → 33 → 53. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔒

60% of holders stayed for 2+ years

■ 60% conviction (2yr+) ■ 18% medium ■ 22% new
139 out of 231 hedge funds have held TWST for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💎

Buying through price weakness — shares +2%, value -24%

Value
-24%
Shares
+2%
Last quarter: funds added +2% more shares while total portfolio value only changed -24%. Institutions were buying while the price was falling — a high-conviction accumulation signal. They're deliberately loading up on the dip.
➡️

Steady discovery — ~53 new funds/quarter

35 → 45 → 35 → 33 → 53 new funds/Q
New funds entering each quarter: 45 → 35 → 33 → 53. Consistent flow of new institutional buyers without clear acceleration or slowdown.
🏛️

Deep conviction — 65% of holders stayed 2+ years

■ 65% veterans ■ 11% 1-2yr ■ 23% new
Of 236 current holders: 154 (65%) have held for over 2 years without selling. These are not momentum buyers — they have lived through drawdowns and stayed. A large veteran base acts as a stabilizing force during selloffs.
✅

Strong quality — 31% AUM from major funds

31% from top-100 AUM funds
35 of 231 holders rank in the top 100 by AUM, accounting for 31% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.
3.1
out of 10
Low Exit Risk
Exit risk score 3.1/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Hedge Fund Ownership: TWST

How many hedge funds hold TWST — quarterly history vs. share price
Quarterly hedge fund ownership of TWST vs. share price

Market Analysis: TWST

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: TWST

-- --
Smart Money Signal ?
Broad Consensus, Selective Conviction

Many quality funds hold this stock, but top-tier positions remain relatively small.

44 top-rated funds 3 high-conviction
Consensus
7.2
/ 10
breadth
×
Elite
3.0
/ 10
conviction
Hedge Fund Positioning: TWST
2026 Q1 Stats Unlock in 20 days 236 + Investors

Track Smart Money conviction in TWST. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2025 Q4) Prior (2025 Q3) Change
Funds Holding 236 223 5.83%
13F Shares 73M 72M 2.27%
Total Value $2.32B $3.05B -24.02%
New Positions 54 33 +21
Increased Positions 78 103 -25
Closed Positions 41 40 +1
Reduced Positions 80 67 +13
Total Calls 5 3 66.67%
Total Puts 3 2 50.0%
PUT/CALL Ratio 0.6 0.67 Bullish

Statistics: TWST

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Valuation Measures Data as of: --

Market Cap --
Enterprise Value --
Trailing P/E --
Forward P/E --
PEG Ratio (5yr expected) --
Price/Sales (ttm) --
Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

Profitability
Profit Margin --
Return on Assets (ttm) --
Return on Equity (ttm) --
Income Statement & Cash Flow
Revenue (ttm) --
Net Income Avi to Common (ttm) --
Diluted EPS (ttm) --
Total Cash (mrq) --
Total Debt/Equity (mrq) --
Levered Free Cash Flow (ttm) --

Institutional Holders (2026 Q1)

236 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in TWST. Verified SEC 13F-HR filings.

Top 25 institutional holders of TWST — 2025 Q4 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 PEREGRINE CAPITAL MANAGEMENT LLC 0.39% 220,079 $10.5M
2 Green Alpha Advisors, LLC 0.25% 5,303 $252K
3 HARBOR CAPITAL ADVISORS, INC. 0.14% 37,399 $2K
4 MRWM Advisors, LLC 0.11% 4,339 $206K
5 PROFUND ADVISORS LLC 0.08% 43,039 $2.0M
6 Conestoga Capital Advisors, LLC 0.05% 56,785 $2.7M
7 Abel Hall, LLC 0.05% 5,009 $238K
8 Sumitomo Mitsui Trust Group, Inc. 0.05% 1,496,099 $71.1M
9 ISTHMUS PARTNERS, LLC 0.05% 9,145 $435K
10 Inspire Investing, LLC 0.04% 11,099 $527K
11 China Universal Asset Management Co., Ltd. 0.04% 10,880 $517K
12 Abacus Wealth Partners, LLC 0.02% 5,545 $263K
13 Ares Financial Consulting, LLC 0.02% 497 $25K
14 E Fund Management Co., Ltd. 0.02% 12,100 $575K
15 AlphaQuest LLC 0.02% 9,455 $300K
16 Pictet Asset Management Holding SA 0.01% 185,992 $8.1M
17 AXXCESS WEALTH MANAGEMENT, LLC 0.01% 5,562 $264K
18 NBC SECURITIES, INC. 0.01% 2,334 $111K
19 EXCHANGE TRADED CONCEPTS, LLC 0.01% 19,992 $950K
20 Police & Firemen's Retirement System of New Jersey 0.01% 16,368 $778K
21 Aberdeen Group plc 0.01% 73,619 $3.5M
22 Handelsbanken Fonder AB 0.00% 25,000 $1K
23 Nuveen, LLC 0.00% 293,655 $14.0M
24 KLP KAPITALFORVALTNING AS 0.00% 13,400 $637K
25 VISION FINANCIAL MARKETS LLC 0.00% 50 $2K
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — TWIST BIOSCIENCE CORP (TWST)

What does the Smart Money Trend signal show for TWST?

Buying streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds added TWST than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for TWST?

Slight buying edge — 52% buying: Last quarter: 123 funds bought or added vs 115 that reduced or exited. It's nearly a 50/50 split — some institutions are convinced, others are taking profits. This mixed picture is normal near price highs.

What is the fund quality score for TWST holders?

Strong quality — 31% AUM from major funds: 35 of 231 holders rank in the top 100 by AUM, accounting for 31% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.

How long have hedge funds held TWST?

60% of holders stayed for 2+ years: 139 out of 231 hedge funds have held TWST for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.