Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Prelude Therapeutics Inc (PRLD)

54 + Investors. Track Smart Money conviction in PRLD. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +6
Streak
2Q ▲
Buyers last Q
64%

Smart Money Signals — PRLD

Based on 54 hedge funds · latest filing: 2026 Q1 · updated quarterly

📈

Buying streak — 2 quarters in a row

last 6Q
For 2 consecutive quarters, more hedge funds added PRLD than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
📊

High ownership — 78% of 3.0Y peak

78% of all-time peak
54 funds currently hold this stock — 78% of the 3.0-year high of 69 funds (reached 2024 Q3). Ownership is elevated but not yet at maximum concentration. Room to grow, but watch if the trend reverses.
📉

Outflows — 5% fewer funds vs a year ago

fund count last 6Q
3 fewer hedge funds hold PRLD compared to a year ago (-5% decline). When institutions consistently reduce their exposure, it's worth exploring the underlying fundamental reasons driving them away.
🟢

More buyers than sellers — 64% buying

32 buying18 selling
Last quarter: 32 funds were net buyers (12 opened a brand new position + 20 added to an existing one). Only 18 were sellers (12 trimmed + 6 sold completely). A clear majority buying is a strong confirmation signal.
➡️

Steady new buyers — ~12 new funds per quarter

new funds entering per quarter
Funds opening this position for the first time: 7 → 4 → 10 → 12. A stable flow of new institutional buyers suggests ongoing interest without signs of either acceleration or slowdown.
🔒

48% of holders stayed for 2+ years

■ 48% conviction (2yr+) ■ 22% medium ■ 30% new
26 out of 54 hedge funds have held PRLD for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💰

Value +30% but shares only +9% — price-driven

Value
+29%
Shares
+8%
Last quarter: the total dollar value of institutional holdings rose +30%, but actual share count only changed +9%. The gap is explained by the stock's price rising — not new buying. Strong value growth with weak share growth means the rally is price momentum, not fresh institutional demand.
📈

Growing discovery — still being found

5 → 7 → 4 → 10 → 12 new funds/Q
New funds entering each quarter: 7 → 4 → 10 → 12. A growing number of institutions are discovering PRLD each quarter. The narrative is still spreading — leaving room for ongoing capital accumulation.
🏛️

Veteran-anchored — 56% veterans vs 27% newcomers

■ 56% veterans ■ 16% 1-2yr ■ 27% new
Entry-cohort mix of 55 holders: 31 (56%) are 2+ year veterans, 9 entered 1–2 years ago, and 15 (27%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
📋

Smaller funds dominant — 7% AUM from top-100

7% from top-100 AUM funds
21 of 54 holders rank in the top 100 by AUM, but together hold only 7% of total institutional value. The stock is held primarily by smaller and mid-sized funds.
2.7
out of 10
Low Exit Risk
Exit risk score 2.7/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — PRLD

In 2026 Q1, 32 hedge funds were net buyers of PRLD (12 opened a new position, 20 added to an existing one), while 18 reduced or exited (12 trimmed, 6 sold completely) — a 64% buyer ratio, indicating clear institutional accumulation. Net buying has persisted for two consecutive quarters, a positive momentum signal. Net fund flow last quarter: +6 funds (more new holders than closures). Total institutional holders: 54.

Hedge Fund Ownership: PRLD

How many hedge funds hold PRLD — quarterly history vs. share price
Quarterly hedge fund ownership of PRLD vs. share price

Market Analysis: PRLD

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: PRLD

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Is It Too Late to Buy Prelude Therapeutics Inc (PRLD) Based on Hedge Fund 13F Filings?

Signal Freshness measures how much PRLD has moved relative to its sector benchmark (XLV) since the 2026 Q1 13F filing. A stock that has barely outrun its sector is still a relatively fresh entry point — the fund's thesis has not yet been priced in by the broader market.

Since Quarter End March 31, 2026 · 79d ago
PRLD
+27.2%
XLV
+2.8%

PRLD outperformed XLV by +24.4% since March 31, 2026.

Since 13F Filing Date May 15, 2026 · 34d ago
PRLD
-2.9%
XLV
+3.9%

Since the filing became public, PRLD outperformed XLV by -6.8% .

Interpretation: The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference. Learn more →

Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

6 top-rated funds 0 high-conviction
Consensus
3.7
/ 10
breadth
×
Elite
0.1
/ 10
conviction
Hedge Fund Positioning: PRLD
54 + Investors

Track Smart Money conviction in PRLD. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q1) Prior (2025 Q4) Change
Funds Holding 54 48 12.5%
13F Shares 31M 29M 8.84%
Total Value $104M $80M 29.54%
New Positions 12 10 +2
Increased Positions 20 14 +6
Closed Positions 6 7 -1
Reduced Positions 11 15 -4
Total Calls 1 0 100%
Total Puts 0 1 -100.0%
PUT/CALL Ratio 0.0 0.0 Bullish

Statistics: PRLD

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Valuation Measures Data as of: --

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PEG Ratio (5yr expected) --
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Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

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Total Cash (mrq) --
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Institutional Holders (2026 Q1)

54 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in PRLD. Verified SEC 13F-HR filings.

QUARTER:
Top 25 PRLD holders by conviction (% of portfolio weight) — 2026 Q1 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Orbimed Advisors LLC 0.74% 10,909,256 $37.3M
2 Kynam Capital Management, LP 0.34% 1,592,551 $5.4M
3 Sphera Funds Management LTD. 0.30% 558,339 $1.9M
4 Baker BROS. Advisors LP 0.20% 10,123,824 $34.6M
5 EcoR1 Capital, LLC 0.14% 947,049 $3.2M
6 ADAR1 Capital Management, LLC 0.03% 152,825 $523K
7 Diametric Capital, LP 0.01% 11,980 $41K
8 NINE MASTS CAPITAL Ltd 0.01% 11,699 $40K
9 Bridgeway Capital Management, LLC 0.00% 53,500 $183K
10 XTX Topco Ltd 0.00% 57,190 $196K
11 Two Sigma Investments, LP 0.00% 923,626 $3.2M
12 Renaissance Technologies LLC 0.00% 275,200 $941K
13 Caldwell Sutter Capital, INC. 0.00% 1,000 $3K
14 Two Sigma Advisers, LP 0.00% 237,300 $688K
15 Marshall Wace, LLP 0.00% 358,906 $1.2M
16 Graham Capital Management, L.P. 0.00% 11,343 $39K
17 Connor, Clark & Lunn Investment Management Ltd. 0.00% 109,085 $373K
18 OMERS ADMINISTRATION Corp 0.00% 32,700 $112K
19 Millennium Management LLC 0.00% 382,737 $1.3M
20 Hrt Financial LP 0.00% 58,699 $200K
21 SBI Securities Co., Ltd. 0.00% 2,641 $9K
22 Focus Partners Wealth 0.00% 50,007 $171K
23 Fortitude Family Office, LLC 0.00% 230 —
24 Cerity Partners LLC 0.00% 32,875 $112K
25 Vanguard Fiduciary Trust Co 0.00% 157,380 $538K
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Prelude Therapeutics Inc (PRLD)

What does the Smart Money Trend signal show for PRLD?

Buying streak — 2 quarters in a row: For 2 consecutive quarters, more hedge funds added PRLD than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for PRLD?

More buyers than sellers — 64% buying: Last quarter: 32 funds were net buyers (12 opened a brand new position + 20 added to an existing one). Only 18 were sellers (12 trimmed + 6 sold completely). A clear majority buying is a strong confirmation signal.

What is the fund quality score for PRLD holders?

Smaller funds dominant — 7% AUM from top-100: 21 of 54 holders rank in the top 100 by AUM, but together hold only 7% of total institutional value. The stock is held primarily by smaller and mid-sized funds.

How long have hedge funds held PRLD?

48% of holders stayed for 2+ years: 26 out of 54 hedge funds have held PRLD for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Is it too late to buy Prelude Therapeutics Inc (PRLD) following the 2026 Q1 hedge fund 13F filings?

As of today, PRLD has moved -2.9% since the 2026 Q1 13F filing date (May 15, 2026), compared to +3.9% for the XLV sector ETF — an outperformance of -6.8%. Since the quarter end (March 31, 2026), PRLD has gained +27.2% vs +2.8% for XLV. The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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