Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

OPKO HEALTH INC (OPK)

214 + Investors. Track Smart Money conviction in OPK. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↓ -8
Streak
1Q ▼
Buyers last Q
39%

Smart Money Signals — OPK

Based on 208 hedge funds · latest filing: 2025 Q4 · updated quarterly

📉

Selling streak — 1 quarter in a row

last 6Q
For 1 consecutive quarter, more hedge funds reduced or closed their OPK positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.
📊

High ownership — 87% of 3.0Y peak

87% of all-time peak
208 funds currently hold this stock — 87% of the 3.0-year high of 240 funds (reached 2025 Q1). Ownership is elevated but not yet at maximum concentration. Room to grow, but watch if the trend reverses.
📉

Outflows — 7% fewer funds vs a year ago

fund count last 6Q
16 fewer hedge funds hold OPK compared to a year ago (-7% decline). When institutions consistently reduce their exposure, it's worth exploring the underlying fundamental reasons driving them away.
🔴

Heavy selling pressure — only 39% buying

71 buying113 selling
Last quarter: 113 funds sold vs only 71 buyers. This is widespread institutional distribution — not a few funds rebalancing, but a broad exit. High conviction bearish signal.
➡️

Steady new buyers — ~30 new funds per quarter

new funds entering per quarter
Funds opening this position for the first time: 43 → 17 → 26 → 30. A stable flow of new institutional buyers suggests ongoing interest without signs of either acceleration or slowdown.
🔒

66% of holders stayed for 2+ years

■ 66% conviction (2yr+) ■ 23% medium ■ 12% new
137 out of 208 hedge funds have held OPK for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💎

Buying through price weakness — shares +1%, value -60%

Value
-60%
Shares
+1%
Last quarter: funds added +1% more shares while total portfolio value only changed -60%. Institutions were buying while the price was falling — a high-conviction accumulation signal. They're deliberately loading up on the dip.
➡️

Steady discovery — ~30 new funds/quarter

28 → 43 → 17 → 26 → 30 new funds/Q
New funds entering each quarter: 43 → 17 → 26 → 30. Consistent flow of new institutional buyers without clear acceleration or slowdown.
🏛️

Deep conviction — 69% of holders stayed 2+ years

■ 69% veterans ■ 15% 1-2yr ■ 16% new
Of 214 current holders: 147 (69%) have held for over 2 years without selling. These are not momentum buyers — they have lived through drawdowns and stayed. A large veteran base acts as a stabilizing force during selloffs.
🏆

Elite ownership — 42% AUM from top-100 funds

42% from top-100 AUM funds
33 of 208 holders are among the 100 largest funds by AUM, controlling 42% of total institutional value in OPK. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.
3.2
out of 10
Low Exit Risk
Exit risk score 3.2/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Hedge Fund Ownership: OPK

How many hedge funds hold OPK — quarterly history vs. share price
Quarterly hedge fund ownership of OPK vs. share price

Market Analysis: OPK

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: OPK

-- --
Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

37 top-rated funds 1 high-conviction
Consensus
6.9
/ 10
breadth
×
Elite
1.2
/ 10
conviction
Hedge Fund Positioning: OPK
2026 Q1 Stats Unlock in 21 days 214 + Investors

Track Smart Money conviction in OPK. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2025 Q4) Prior (2025 Q3) Change
Funds Holding 214 223 -4.04%
13F Shares 200M 197M 1.2%
Total Value $251M $626M -59.96%
New Positions 30 26 +4
Increased Positions 50 79 -29
Closed Positions 38 17 +21
Reduced Positions 83 72 +11
Total Calls 7 7 -
Total Puts 2 3 -33.33%
PUT/CALL Ratio 0.29 0.43 Bullish

Statistics: OPK

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Valuation Measures Data as of: --

Market Cap --
Enterprise Value --
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Forward P/E --
PEG Ratio (5yr expected) --
Price/Sales (ttm) --
Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

Profitability
Profit Margin --
Return on Assets (ttm) --
Return on Equity (ttm) --
Income Statement & Cash Flow
Revenue (ttm) --
Net Income Avi to Common (ttm) --
Diluted EPS (ttm) --
Total Cash (mrq) --
Total Debt/Equity (mrq) --
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Institutional Holders (2026 Q1)

214 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in OPK. Verified SEC 13F-HR filings.

Top 25 institutional holders of OPK — 2025 Q4 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 WASHINGTON GROWTH STRATEGIES LLC 1.01% 1,356,124 $1.5M
2 PFG Investments, LLC 0.06% 1,112,776 $1.3M
3 HIGHLINE WEALTH PARTNERS LLC 0.03% 116,680 $133K
4 OP Asset Management Ltd 0.02% 1,102,254 $1.5M
5 CUMBERLAND ADVISORS INC 0.01% 19,500 $22K
6 Abel Hall, LLC 0.01% 33,271 $38K
7 Westmount Partners, LLC 0.01% 18,550 $21K
8 Colony Family Offices, LLC 0.00% 14,729 $17K
9 U.S. Capital Wealth Advisors, LLC 0.00% 133,261 $152K
10 Greenbush Financial Group, LLC 0.00% 10,000 $11K
11 Key FInancial Inc 0.00% 13,250 $15K
12 Formidable Asset Management, LLC 0.00% 10,296 $13K
13 MOODY NATIONAL BANK TRUST DIVISION 0.00% 13,554 $15K
14 SAX WEALTH ADVISORS, LLC 0.00% 20,188 $25K
15 World Investment Advisors 0.00% 66,520 $76K
16 Assenagon Asset Management S.A. 0.00% 652,066 $740K
17 TRAPHAGEN INVESTMENT ADVISORS LLC 0.00% 11,680 $13K
18 KESTRA PRIVATE WEALTH SERVICES, LLC 0.00% 58,450 $67K
19 COMMONWEALTH EQUITY SERVICES, LLC 0.00% 430,906 $491K
20 PFS Partners, LLC 0.00% 1,100 $1K
21 Apella Capital, LLC 0.00% 27,021 $34K
22 CAPITAL ADVISORS INC/OK 0.00% 20,000 $23K
23 Sterling Capital Management LLC 0.00% 13,716 $16K
24 Private Advisor Group, LLC 0.00% 55,301 $63K
25 ProShare Advisors LLC 0.00% 140,658 $160K
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — OPKO HEALTH INC (OPK)

What does the Smart Money Trend signal show for OPK?

Selling streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds reduced or closed their OPK positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.

What is the institutional breadth score for OPK?

Heavy selling pressure — only 39% buying: Last quarter: 113 funds sold vs only 71 buyers. This is widespread institutional distribution — not a few funds rebalancing, but a broad exit. High conviction bearish signal.

What is the fund quality score for OPK holders?

Elite ownership — 42% AUM from top-100 funds: 33 of 208 holders are among the 100 largest funds by AUM, controlling 42% of total institutional value in OPK. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held OPK?

66% of holders stayed for 2+ years: 137 out of 208 hedge funds have held OPK for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.