Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Mereo Biopharma Group plc (MREO)

62 + Investors. Track Smart Money conviction in MREO. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↓ -10
Streak
2Q ▼
Buyers last Q
42%

Smart Money Signals — MREO

Based on 62 hedge funds · latest filing: 2026 Q1 · updated quarterly

📉

Selling streak — 2 quarters in a row

last 6Q
For 2 consecutive quarters, more hedge funds reduced or closed their MREO positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.
📊

High ownership — 70% of 3.0Y peak

70% of all-time peak
62 funds currently hold this stock — 70% of the 3.0-year high of 89 funds (reached 2024 Q4). Ownership is elevated but not yet at maximum concentration. Room to grow, but watch if the trend reverses.
📉

Outflows — 30% fewer funds vs a year ago

fund count last 6Q
26 fewer hedge funds hold MREO compared to a year ago (-30% decline). When institutions consistently reduce their exposure, it's worth exploring the underlying fundamental reasons driving them away.
🟠

More sellers than buyers — 42% buying

29 buying40 selling
Last quarter: 40 funds reduced or exited vs 29 that bought or added. When more than half of active funds are selling, it's a caution flag — especially if the stock price hasn't moved down yet.
⚠️

Fewer new buyers each quarter (-9 vs last Q)

new funds entering per quarter
Funds opening this position for the first time: 12 → 17 → 21 → 12. Each quarter fewer new institutions are entering. This usually means most funds that wanted in are already in — the stock is well-known but the pool of potential new buyers is shrinking.
🔒

53% of holders stayed for 2+ years

■ 53% conviction (2yr+) ■ 19% medium ■ 27% new
33 out of 62 hedge funds have held MREO for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💎

Buying through price weakness — shares +15%, value -9%

Value
-9%
Shares
+14%
Last quarter: funds added +15% more shares while total portfolio value only changed -9%. Institutions were buying while the price was falling — a high-conviction accumulation signal. They're deliberately loading up on the dip.
📈

Growing discovery — still being found

13 → 12 → 17 → 21 → 12 new funds/Q
New funds entering each quarter: 12 → 17 → 21 → 12. A growing number of institutions are discovering MREO each quarter. The narrative is still spreading — leaving room for ongoing capital accumulation.
🏛️

Veteran-anchored — 63% veterans vs 30% newcomers

■ 63% veterans ■ 7% 1-2yr ■ 30% new
Entry-cohort mix of 67 holders: 42 (63%) are 2+ year veterans, 5 entered 1–2 years ago, and 20 (30%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
📋

Smaller funds dominant — 18% AUM from top-100

18% from top-100 AUM funds
12 of 61 holders rank in the top 100 by AUM, but together hold only 18% of total institutional value. The stock is held primarily by smaller and mid-sized funds.
2.6
out of 10
Low Exit Risk
Exit risk score 2.6/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — MREO

In 2026 Q1, 29 hedge funds were net buyers of MREO (12 opened a new position, 17 added to an existing one), while 40 reduced or exited (18 trimmed, 22 sold completely) — a 42% buyer ratio, indicating roughly balanced activity. Net selling has persisted for two consecutive quarters. Net fund flow last quarter: -10 funds (more exits than new entries). Total institutional holders: 62.

Hedge Fund Ownership: MREO

How many hedge funds hold MREO — quarterly history vs. share price
Quarterly hedge fund ownership of MREO vs. share price

Market Analysis: MREO

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: MREO

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Is It Too Late to Buy Mereo Biopharma Group plc (MREO) Based on Hedge Fund 13F Filings?

Signal Freshness measures how much MREO has moved relative to its sector benchmark (XLV) since the 2026 Q1 13F filing. A stock that has barely outrun its sector is still a relatively fresh entry point — the fund's thesis has not yet been priced in by the broader market.

Since Quarter End March 31, 2026 · 81d ago
MREO
-6.4%
XLV
+2.1%

MREO outperformed XLV by -8.5% since March 31, 2026.

Since 13F Filing Date May 15, 2026 · 36d ago
MREO
+28.7%
XLV
+3.2%

Since the filing became public, MREO outperformed XLV by +25.5% .

Interpretation: The stock has significantly outperformed its sector benchmark — the original entry opportunity has largely been captured by earlier investors. Learn more →

Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

4 top-rated funds 0 high-conviction
Consensus
3.0
/ 10
breadth
×
Elite
0.3
/ 10
conviction
Hedge Fund Positioning: MREO
62 + Investors

Track Smart Money conviction in MREO. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q1) Prior (2025 Q4) Change
Funds Holding 62 72 -13.89%
13F Shares 77M 67M 14.63%
Total Value $25M $28M -9.37%
New Positions 12 21 -9
Increased Positions 15 20 -5
Closed Positions 22 34 -12
Reduced Positions 18 19 -1
Total Calls 3 6 -50.0%
Total Puts 3 3 -
PUT/CALL Ratio 1.0 0.5 Neutral

Statistics: MREO

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Valuation Measures Data as of: --

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PEG Ratio (5yr expected) --
Price/Sales (ttm) --
Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

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Profit Margin --
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Income Statement & Cash Flow
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Diluted EPS (ttm) --
Total Cash (mrq) --
Total Debt/Equity (mrq) --
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Institutional Holders (2026 Q1)

62 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in MREO. Verified SEC 13F-HR filings.

QUARTER:
Top 25 MREO holders by conviction (% of portfolio weight) — 2026 Q1 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Defilade Capital Management, L.P. 0.35% 7,558,756 $2.5M
2 Newtyn Management, LLC 0.25% 7,079,056 $2.3M
3 Tejara Capital Ltd 0.22% 2,037,520 $672K
4 683 Capital Management, LLC 0.21% 12,000,000 $4.0M
5 EcoR1 Capital, LLC 0.19% 13,368,855 $4.4M
6 Rangeley Capital, LLC 0.11% 329,200 $109K
7 Knott David M Jr 0.06% 300,337 $99K
8 Rubric Capital Management LP 0.05% 15,307,347 $5.1M
9 Forefront Analytics, LLC 0.04% 127,778 $42K
10 Virtus Investment Advisers, LLC 0.01% 125,662 $41K
11 Significant Wealth Partners LLC 0.01% 25,634 $8K
12 SmartHarvest Portfolios, LLC 0.01% 49,512 $16K
13 Three Magnolias Financial Advisors, LLC 0.00% 19,000 $6K
14 ADAR1 Capital Management, LLC 0.00% 150,000 $50K
15 Wealthspire Advisors, LLC 0.00% 796,036 $263K
16 NFSG Corp 0.00% 18,750 $6K
17 Clear Harbor Asset Management, LLC 0.00% 35,000 $12K
18 StoneX Group Inc. 0.00% 36,873 $12K
19 Astoria Portfolio Advisors LLC. 0.00% 10,000 $3K
20 Millennium Management LLC 0.00% 3,559,103 $1.2M
21 XTX Topco Ltd 0.00% 84,469 $28K
22 GAMMA Investing LLC 0.00% 19,274 $6K
23 Marshall Wace, LLP 0.00% 686,987 $227K
24 Group One Trading LLC 0.00% 335,827 $111K
25 Baader Bank Aktiengesellschaft 0.00% 12,330 $3K
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Mereo Biopharma Group plc (MREO)

What does the Smart Money Trend signal show for MREO?

Selling streak — 2 quarters in a row: For 2 consecutive quarters, more hedge funds reduced or closed their MREO positions than added to them. Sustained institutional selling is a meaningful warning sign — these are professionals with deep research teams collectively deciding to exit.

What is the institutional breadth score for MREO?

More sellers than buyers — 42% buying: Last quarter: 40 funds reduced or exited vs 29 that bought or added. When more than half of active funds are selling, it's a caution flag — especially if the stock price hasn't moved down yet.

What is the fund quality score for MREO holders?

Smaller funds dominant — 18% AUM from top-100: 12 of 61 holders rank in the top 100 by AUM, but together hold only 18% of total institutional value. The stock is held primarily by smaller and mid-sized funds.

How long have hedge funds held MREO?

53% of holders stayed for 2+ years: 33 out of 62 hedge funds have held MREO for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Is it too late to buy Mereo Biopharma Group plc (MREO) following the 2026 Q1 hedge fund 13F filings?

As of today, MREO has moved +28.7% since the 2026 Q1 13F filing date (May 15, 2026), compared to +3.2% for the XLV sector ETF — an outperformance of +25.5%. Since the quarter end (March 31, 2026), MREO has gained -6.4% vs +2.1% for XLV. The stock has significantly outperformed its sector benchmark — the original entry opportunity has largely been captured by earlier investors.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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