Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Lexicon Pharmaceuticals Inc (LXRX)

134 + Investors. Track Smart Money conviction in LXRX. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +16
Streak
1Q ▲
Buyers last Q
61%

Smart Money Signals — LXRX

Based on 135 hedge funds · latest filing: 2026 Q1 · updated quarterly

📈

Buying streak — 1 quarter in a row

last 6Q
For 1 consecutive quarter, more hedge funds added LXRX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
135 hedge funds hold LXRX right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
📶

Steady growth — +8% more funds vs a year ago

fund count last 6Q
+10 new funds entered over the past year (+8% YoY). Gradual, steady growth in institutional ownership is generally a healthy signal — not a speculative rush, but consistent conviction.
🟢

More buyers than sellers — 61% buying

72 buying46 selling
Last quarter: 72 funds were net buyers (32 opened a brand new position + 40 added to an existing one). Only 46 were sellers (30 trimmed + 16 sold completely). A clear majority buying is a strong confirmation signal.
📈

More new buyers each quarter (+13 vs last Q)

new funds entering per quarter
Funds opening a new LXRX position: 27 → 21 → 19 → 32. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔒

47% of holders stayed for 2+ years

■ 47% conviction (2yr+) ■ 24% medium ■ 30% new
63 out of 135 hedge funds have held LXRX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
💰

Value +68% but shares only +24% — price-driven

Value
+68%
Shares
+24%
Last quarter: the total dollar value of institutional holdings rose +68%, but actual share count only changed +24%. The gap is explained by the stock's price rising — not new buying. Strong value growth with weak share growth means the rally is price momentum, not fresh institutional demand.
➡️

Steady discovery — ~32 new funds/quarter

32 → 27 → 21 → 19 → 32 new funds/Q
New funds entering each quarter: 27 → 21 → 19 → 32. Consistent flow of new institutional buyers without clear acceleration or slowdown.
🏛️

Veteran-anchored — 59% veterans vs 33% newcomers

■ 59% veterans ■ 9% 1-2yr ■ 33% new
Entry-cohort mix of 141 holders: 83 (59%) are 2+ year veterans, 12 entered 1–2 years ago, and 46 (33%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
✅

Strong quality — 21% AUM from major funds

21% from top-100 AUM funds
27 of 134 holders rank in the top 100 by AUM, accounting for 21% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.
3.8
out of 10
Low Exit Risk
Exit risk score 3.8/10 — low institutional crowding. Ownership is below peak levels, holder base is relatively sticky, and buying momentum is positive.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — LXRX

In 2026 Q1, 72 hedge funds were net buyers of LXRX (32 opened a new position, 40 added to an existing one), while 46 reduced or exited (30 trimmed, 16 sold completely) — a 61% buyer ratio, indicating clear institutional accumulation. 21% of total institutional value in LXRX is held by top-100 AUM funds, reflecting strong institutional quality. Net fund flow last quarter: +16 funds (more new holders than closures). Total institutional holders: 135.

Hedge Fund Ownership: LXRX

How many hedge funds hold LXRX — quarterly history vs. share price
Quarterly hedge fund ownership of LXRX vs. share price

Market Analysis: LXRX

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: LXRX

-- --

Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Is It Too Late to Buy Lexicon Pharmaceuticals Inc (LXRX) Based on Hedge Fund 13F Filings?

Signal Freshness measures how much LXRX has moved relative to its sector benchmark (XLV) since the 2026 Q1 13F filing. A stock that has barely outrun its sector is still a relatively fresh entry point — the fund's thesis has not yet been priced in by the broader market.

Since Quarter End March 31, 2026 · 80d ago
LXRX
nan%
XLV
+2.1%

LXRX outperformed XLV by nan% since March 31, 2026.

Since 13F Filing Date May 15, 2026 · 35d ago
LXRX
nan%
XLV
+3.2%

Since the filing became public, LXRX outperformed XLV by nan% .

Interpretation: The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference. Learn more →

Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

11 top-rated funds 0 high-conviction
Consensus
4.7
/ 10
breadth
×
Elite
1.1
/ 10
conviction
Hedge Fund Positioning: LXRX
134 + Investors

Track Smart Money conviction in LXRX. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q1) Prior (2025 Q4) Change
Funds Holding 134 119 12.61%
13F Shares 325M 261M 24.44%
Total Value $505M $301M 68.05%
New Positions 31 19 +12
Increased Positions 39 30 +9
Closed Positions 16 22 -6
Reduced Positions 28 40 -12
Total Calls 3 3 -
Total Puts 3 2 50.0%
PUT/CALL Ratio 1.0 0.67 Neutral

Statistics: LXRX

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Valuation Measures Data as of: --

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PEG Ratio (5yr expected) --
Price/Sales (ttm) --
Price/Book (mrq) --
Enterprise Value/Revenue --
Enterprise Value/EBITDA --
Beta (5Y Monthly) --
Short Ratio (Days to Cover) --
Short % of Float --

Financial Highlights

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Net Income Avi to Common (ttm) --
Diluted EPS (ttm) --
Total Cash (mrq) --
Total Debt/Equity (mrq) --
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Institutional Holders (2026 Q1)

134 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in LXRX. Verified SEC 13F-HR filings.

QUARTER:
Top 25 LXRX holders by conviction (% of portfolio weight) — 2026 Q1 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Artal Group S.A. 23.89% 154,734,327 $241.4M
2 Siren, L.L.C. 1.92% 44,303,518 $69.1M
3 Ishara Investments LP 1.33% 902,000 $1.4M
4 Sessa Capital IM, L.P. 0.51% 17,912,961 $27.9M
5 Quantessence Capital LLC 0.14% 18,581 $29K
6 ADAR1 Capital Management, LLC 0.07% 750,000 $1.2M
7 CTC Alternative Strategies, Ltd. 0.06% 17,544 $27K
8 R Squared Ltd 0.06% 67,526 $105K
9 Catalyst Funds Management Pty Ltd 0.05% 207,900 $324K
10 Hennion & Walsh Asset Management, Inc. 0.04% 848,138 $1.3M
11 Headlands Technologies LLC 0.03% 191,322 $298K
12 Tang Capital Management LLC 0.03% 399,700 $624K
13 Quarry LP 0.03% 110,000 $172K
14 Diker Management LLC 0.03% 20,000 $31K
15 Diametric Capital, LP 0.03% 67,841 $106K
16 Straight Path Wealth Management 0.03% 62,666 $98K
17 Security National Bank of Sioux City Iowa /Ia/ 0.02% 26,650 $42K
18 EntryPoint Capital, LLC 0.02% 48,498 $76K
19 Ikarian Capital, LLC 0.02% 164,674 $257K
20 Invera Wealth Advisors, LLC 0.02% 20,000 $31K
21 Point72 Asset Management, L.P. 0.02% 7,814,606 $12.2M
22 Fortis Group Advisors, LLC 0.01% 50,000 $80K
23 Talisman Wealth Advisors LLC 0.01% 10,000 $16K
24 Bridgewater Advisors Inc. 0.01% 82,209 $201K
25 Compagnie Lombard Odier SCmA 0.01% 510,000 $796K
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Lexicon Pharmaceuticals Inc (LXRX)

What does the Smart Money Trend signal show for LXRX?

Buying streak — 1 quarter in a row: For 1 consecutive quarter, more hedge funds added LXRX than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for LXRX?

More buyers than sellers — 61% buying: Last quarter: 72 funds were net buyers (32 opened a brand new position + 40 added to an existing one). Only 46 were sellers (30 trimmed + 16 sold completely). A clear majority buying is a strong confirmation signal.

What is the fund quality score for LXRX holders?

Strong quality — 21% AUM from major funds: 27 of 134 holders rank in the top 100 by AUM, accounting for 21% of total institutional value held. A meaningful share of the ownership value comes from the most well-resourced institutions.

How long have hedge funds held LXRX?

47% of holders stayed for 2+ years: 63 out of 135 hedge funds have held LXRX for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Is it too late to buy Lexicon Pharmaceuticals Inc (LXRX) following the 2026 Q1 hedge fund 13F filings?

As of today, LXRX has moved nan% since the 2026 Q1 13F filing date (May 15, 2026), compared to +3.2% for the XLV sector ETF — an outperformance of nan%. Since the quarter end (March 31, 2026), LXRX has gained nan% vs +2.1% for XLV. The stock is tracking its sector benchmark closely. The signal remains fresh and the entry point is still near the fund's implied reference.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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