Stock Analysis
Data Source: SEC EDGAR 13F
Updated Hourly

Krystal Biotech Inc (KRYS)

414 + Investors. Track Smart Money conviction in KRYS. See who's accumulating, reducing, or initiating positions.

Current Price
-- USD
Analyst Target
-- (0 analysts)
Upside
0.00%
Net Flow Q/Q
↑ +56
Streak
4Q ▲
Buyers last Q
65%

Smart Money Signals — KRYS

Based on 423 hedge funds · latest filing: 2026 Q2 · updated quarterly

📈

Buying streak — 4 quarters in a row

last 6Q
For 4 consecutive quarters, more hedge funds added KRYS than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.
🏔️

At the ownership peak (100% of max)

100% of all-time peak
423 hedge funds hold KRYS right now — the highest count in 3.0 years. When ownership is this concentrated, any bad news can trigger a chain reaction: one big fund sells, others follow. This is a classic 'crowded trade' — high popularity doesn't equal safety.
🚀

Fast accumulation — +54% more funds vs a year ago

fund count last 6Q
+149 new funds entered over the past year (+54% YoY). That's a rapid rush of institutional money. Fast accumulation often signals a major thesis — but it also means the stock could fall quickly if that thesis breaks.
🟢

More buyers than sellers — 65% buying

275 buying151 selling
Last quarter: 275 funds were net buyers (97 opened a brand new position + 178 added to an existing one). Only 151 were sellers (110 trimmed + 41 sold completely). A clear majority buying is a strong confirmation signal.
📈

More new buyers each quarter (+22 vs last Q)

new funds entering per quarter
Funds opening a new KRYS position: 45 → 86 → 75 → 97. A growing influx of new institutional buyers means the asset is still gathering momentum — the consensus hasn't fully saturated yet.
🔒

41% of holders stayed for 2+ years

■ 41% conviction (2yr+) ■ 22% medium ■ 37% new
174 out of 423 hedge funds have held KRYS for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.
📈

Growing discovery — still being found

45 → 45 → 86 → 75 → 97 new funds/Q
New funds entering each quarter: 45 → 86 → 75 → 97. A growing number of institutions are discovering KRYS each quarter. The narrative is still spreading — leaving room for ongoing capital accumulation.
🏛️

Veteran-anchored — 44% veterans vs 38% newcomers

■ 44% veterans ■ 17% 1-2yr ■ 38% new
Entry-cohort mix of 437 holders: 193 (44%) are 2+ year veterans, 76 entered 1–2 years ago, and 168 (38%) joined within the past year. A veteran-weighted cap table skews toward institutional memory over fresh momentum.
🏆

Elite ownership — 56% AUM from top-100 funds

56% from top-100 AUM funds
55 of 419 holders are among the 100 largest funds by AUM, controlling 56% of total institutional value in KRYS. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.
4.6
out of 10
Moderate Exit Risk
Exit risk score 4.6/10 — some crowding factors present, but no critical concentration. Watch ownership trend over the next 1–2 quarters for direction.

Methodology note: these Smart Money cards use consecutive 13F disclosure snapshots, not trade-by-trade execution data. "Buying", "selling", "new holders", and "trimmed" refer to quarter-over-quarter changes in reported holders, aggregate shares, or disclosed position values between filings. They are useful for ownership regime analysis and crowding, but they do not imply exact trade timing on the filing date.

Institutional Sentiment Summary — KRYS

In 2026 Q2, 275 hedge funds were net buyers of KRYS (97 opened a new position, 178 added to an existing one), while 151 reduced or exited (110 trimmed, 41 sold completely) — a 65% buyer ratio, indicating clear institutional accumulation. This marks 4 consecutive quarters of net institutional buying — a persistent conviction signal. 56% of total institutional value in KRYS is held by top-100 AUM funds, reflecting elite-tier ownership quality. Net fund flow last quarter: +56 funds (more new holders than closures). Total institutional holders: 423.

Hedge Fund Ownership: KRYS

How many hedge funds hold KRYS — quarterly history vs. share price
Quarterly hedge fund ownership of KRYS vs. share price

Market Analysis: KRYS

Analyst Price Targets

Avg. Price Target
--

Analyst Recommendations

Stock Performance

Real-time

Company Profile: KRYS

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Institutional ownership data sourced from SEC EDGAR Form 13F-HR filings.

Loading signal freshness…
Smart Money Signal ?
Limited Smart Money Interest

No strong consensus or elite conviction detected among institutional holders.

17 top-rated funds 3 high-conviction
Consensus
5.5
/ 10
breadth
×
Elite
4.0
/ 10
conviction
Hedge Fund Positioning: KRYS
414 + Investors

Track Smart Money conviction in KRYS. See who's accumulating, reducing, or initiating positions.

Metric All 13F Filers (2026 Q2) Prior (2026 Q1) Change
Funds Holding 414 367 12.81%
13F Shares 31M 29M 6.26%
Total Value $10.72B $7.19B 48.96%
New Positions 95 75 +20
Increased Positions 174 140 +34
Closed Positions 44 42 +2
Reduced Positions 104 102 +2
Total Calls 9 6 50.0%
Total Puts 9 6 50.0%
PUT/CALL Ratio 1.0 1.0 Neutral

Statistics: KRYS

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Institutional Holders (2026 Q2)

414 + investors

Explore institutional interest and hedge fund ownership dynamics. Analyze portfolio weights, new positions, and conviction trends in KRYS. Verified SEC 13F-HR filings.

QUARTER:
Top 25 KRYS holders by conviction (% of portfolio weight) — 2026 Q2 · Source: SEC Form 13F
# Investor % of Portfolio Shares Mkt Value
1 Redmile Group, LLC 15.77% 632,005 $234.9M
2 Soleus Capital Management, L.P. 12.03% 939,254 $349.1M
3 Act Capital Management, LLC 10.93% 45,000 $16.7M
4 Avoro Capital Advisors LLC 9.64% 2,888,888 $1.07B
5 S Squared Technology, LLC 8.94% 77,545 $28.8M
6 Evolutionary Tree Capital Management, LLC 5.82% 8,301 $3.1M
7 Palisades Investment Partners, LLC 5.05% 47,801 $17.8M
8 Frazier Life Sciences Management, L.P. 3.90% 481,307 $178.9M
9 Biondo Investment Advisors, LLC 3.23% 70,945 $26.4M
10 Atle Fund Management AB 2.40% 24,019 $8.9M
11 Elmind Capital, LP 2.05% 22,000 $8.2M
12 Hood River Capital Management LLC 1.79% 663,375 $246.6M
13 Braidwell LP 1.77% 128,975 $47.9M
14 Lisanti Capital Growth, LLC 1.56% 19,050 $7.1M
15 Tetragon Partners GP Ltd 1.15% 19,668 $7.3M
16 Nantahala Capital Management, LLC 1.05% 85,000 $31.6M
17 Bridge City Capital, LLC 1.00% 11,816 $4.4M
18 Hanseatic Management Services Inc 0.85% 3,120 $1.2M
19 Brown Capital Management LLC 0.81% 10,968 $4.1M
20 Privium Fund Management B.V. 0.76% 11,170 $4.2M
21 Cim, LLC 0.75% 15,703 $5.8M
22 William Blair Investment Management, LLC 0.64% 570,153 $211.9M
23 Granite Investment Partners, LLC 0.63% 32,837 $12.2M
24 AlphaCentric Advisors LLC 0.61% 1,945 $723K
25 Torray Investment Partners LLC 0.61% 12,156 $4.5M
Investor Ownership
History 		% of Portfolio Prev % Rank Conviction Avg Buy Price 13F Score™ 3Y / 7Y Sell Timing Shares Mkt Value Change Change % Source Quarter Filed

Frequently Asked Questions — Krystal Biotech Inc (KRYS)

What does the Smart Money Trend signal show for KRYS?

Buying streak — 4 quarters in a row: For 4 consecutive quarters, more hedge funds added KRYS than sold it. That's a consistent pattern of professional buying — not a one-time trade. When institutions keep buying quarter after quarter, it usually means they see a multi-year opportunity, not just a short-term momentum flip.

What is the institutional breadth score for KRYS?

More buyers than sellers — 65% buying: Last quarter: 275 funds were net buyers (97 opened a brand new position + 178 added to an existing one). Only 151 were sellers (110 trimmed + 41 sold completely). A clear majority buying is a strong confirmation signal.

What is the fund quality score for KRYS holders?

Elite ownership — 56% AUM from top-100 funds: 55 of 419 holders are among the 100 largest funds by AUM, controlling 56% of total institutional value in KRYS. When the biggest players dominate the cap table, it signifies deep institutional support — since mega-funds deploy the most rigorous due diligence and capital.

How long have hedge funds held KRYS?

41% of holders stayed for 2+ years: 174 out of 423 hedge funds have held KRYS for over 2 years without selling. Long-term investors are generally harder to shake out during market stress, creating a stable ownership base that limits the risk of sudden capitulation.

Where does this institutional ownership data come from?

All holdings data is sourced from SEC Form 13F filings, which institutional investment managers with over $100 million in assets are required to submit quarterly. Data is parsed directly from SEC EDGAR.

Disclaimer: The information on this page is for informational purposes only and does not constitute investment advice, a recommendation, or an offer to buy or sell any security. Institutional holdings data is sourced from SEC Form 13F filings and reflects positions as of the filing date. Past performance of any fund or portfolio is not indicative of future results. 13Foresight is not a registered investment adviser. Always conduct your own due diligence before making investment decisions.

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