TWO SIGMA INVESTMENTS, LP reported APPLIED THERAPEUTICS INC (APLT) in 19 quarterly 13F filings from 2023 Q4 through 2025 Q3. The latest visible filing shows APLT at 0.00% of the fund.
This page tracks quarterly shares, estimated market value, portfolio weight, filing dates, and disclosure-aligned stock prices directly from SEC EDGAR 13F filings. Older history is available after unlock; the visible window still shows the most recent pattern.
This page is designed to answer the real investor question behind a 13F filing: how meaningful was TWO SIGMA INVESTMENTS, LP's position in APPLIED THERAPEUTICS INC, and how did that conviction change over time? You can read the holding window, peak weight, latest reported size, disclosure timing, and quarter-by-quarter changes without piecing the story together from raw SEC rows.
APLT was reported at 0.00% of portfolio in the most recent visible filing.
Peak weight helps separate a token disclosure from a real conviction holding the fund genuinely cared about.
Longer holding windows often tell a very different story from short-lived tactical trades or one-quarter experiments.
Knowing that a fund owned a stock is useful. Knowing whether it was a 0.20% placeholder or a true high-conviction position is where the signal actually starts.
These are the practical questions this page is built to answer before you even open the full history table.
TWO SIGMA INVESTMENTS, LP reported APLT across 7 quarterly 13F filings, from 2023 Q4 through 2025 Q3.
The largest reported portfolio weight for APLT was 0.00% in 2024 Q1.
The most recent filing on this page is 2025 Q3, when TWO SIGMA INVESTMENTS, LP reported 198,933 shares, equal to 0.00% of portfolio, with an estimated market value of $120K.
The chart compares TWO SIGMA INVESTMENTS, LP's quarterly APLT portfolio weight with the stock's indexed share price, so you can see whether the fund was building, trimming, or holding the position as price moved.