Foresite Capital Management IV, LLC

All Holdings — 2025 Q4

AI Portfolio Summary
In 2025 Q4, Foresite Capital Management IV, LLC maintained a portfolio of 7 distinct positions. The most significant new addition to the portfolio was Alector, Inc., which now represents 2.64% of the total fund value.
PCA Score Concentration Risk
Risk ENB
Total Positions
7
Quarter
2025 Q4
Top Holding
PHVS (57.7%)
Top 10 Concentration
100.0%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-7 of 7
Stock History Sector / Type Port % Prev % Rank / Prev Conviction Change % Change Influence Shares Mkt Value Avg Cost Price Held 1st Owned Source Source Date Date Reported
PHVS
Pharvaris N.V.
Healthcare 57.73% 65.29% #1
Prev: #1
7.0 no change no change
P
S
4,778,581 $132,605,623 2021 Q1 13F Filing 2025-12-31 2026-02-14 (Est.)
CYTK
CYTOKINETICS IN...
Healthcare 12.68% 13.79% #2
Prev: #2
6.5 no change no change
P
S
458,295 $29,120,064 2018 Q4 13F Filing 2025-12-31 2026-02-14 (Est.)
LYEL
Lyell Immunopha...
Healthcare 10.72% 7.12% #3 1
Prev: #4
6.0 no change no change
P
S
800,399 $24,636,281 2021 Q2 13F Filing 2025-12-31 2026-02-14 (Est.)
MAZE
Maze Therapeuti...
Healthcare 9.43% 7.42% #4 1
Prev: #3
5.3 no change no change
P
S
522,657 $21,653,680 2025 Q1 13F Filing 2025-12-31 2026-02-14 (Est.)
RLAY
Relay Therapeut...
Healthcare 3.68% 2.86% #5 1
Prev: #6
3.0 no change no change
P
S
1,000,000 $8,460,000 2020 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
XENE
Xenon Pharmaceu...
Healthcare 3.12% 3.52% #6 1
Prev: #5
2.2 no change no change
P
S
160,000 $7,171,200 2018 Q3 13F Filing 2025-12-31 2026-02-14 (Est.)
ALEC
Alector, Inc.
Healthcare 2.64% #7
Prev: #—
4.6 3,887,200 no change
NEW
3,887,200 $6,064,032 2019 Q1 13F Filing 2025-12-31 2026-02-14 (Est.)
Showing 1-7 of 7 holdings

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