Foresite Capital Management IV, LLC — 13F Holdings

2026 Q1  ·  8 Positions

2026 Q1 Portfolio Activity

In 2026 Q1, Foresite Capital Management IV, LLC maintained a portfolio of 8 distinct positions. The most significant new addition was Eikon Therapeutics, Inc., now representing 8.67% of the total fund value. They heavily accumulated shares in CYTOKINETICS INC, increasing the position by 9.8%. The fund also reduced its exposure to Maze Therapeutics, Inc. by 70.0%.
Position History hover any row below to update
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Foresite Capital Management IV, LLC San Francisco, CA Venture Capital / Crossover Fund AUM $237M
Fund Overview SEC EDGAR
PCA Score Concentration Risk
Risk ENB
To Excel To CSV
Total Positions
8
Quarter
2026 Q1
Top Holding
PHVS (56.9%)
Top 10 Concentration
100.0%
Turnover Rate
23.4%
Sector HHI
0.18
Items per page:
Showing 1-8 of 8
Stock History Sector / Type Port % Prev % Rank / Prev Conviction
Freshness
Change % Change Influence Shares Mkt Value Avg Cost Price Held 1st Owned Source Source Date Date Reported
PHVS
Pharvaris N.V.
Healthcare 56.94% 57.73% #1
Prev: #1
7.0
—
no change no change
P
S
4,778,581 $134,994,913 2021 Q1 13F Filing 2026-03-31 2026-05-15
CYTK
CYTOKINETICS IN...
Healthcare 13.99% 12.68% #2
Prev: #2
7.5
—
45,000 9.8%
P
S
503,295 $33,172,173 2018 Q4 13F Filing 2026-03-31 2026-05-15
N/A
Eikon Therapeut...
Unknown 8.67% — #3
Prev: #—
8.0
—
1,943,682 —
NEW
 1,943,682 $20,564,156 — 13F Filing 2026-03-31 2026-05-15
LYEL
Lyell Immunopha...
Healthcare 6.77% 10.72% #4 1
Prev: #3
4.2
—
no change no change
P
S
800,399 $16,056,004 2021 Q2 13F Filing 2026-03-31 2026-05-15
RLAY
Relay Therapeut...
Healthcare 4.20% 3.68% #5
Prev: #5
3.2
—
no change no change
P
S
1,000,000 $9,950,000 2020 Q3 13F Filing 2026-03-31 2026-05-15
XENE
Xenon Pharmaceu...
Healthcare 3.92% 3.12% #6
Prev: #6
2.6
—
no change no change
P
S
160,000 $9,304,000 2018 Q3 13F Filing 2026-03-31 2026-05-15
ALEC
Alector, Inc.
Healthcare 3.53% 2.64% #7
Prev: #7
2.4
—
no change no change
P
S
3,887,200 $8,357,480 2019 Q1 13F Filing 2026-03-31 2026-05-15
MAZE
Maze Therapeuti...
Healthcare 1.98% 9.43% #8 4
Prev: #4
0.8
—
-365,756 -70.0%
P
S
156,901 $4,683,495 2025 Q1 13F Filing 2026-03-31 2026-05-15
Showing 1-8 of 8 holdings

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